著者
Hiroaki Kawano Tetsufumi Motokawa Hirokazu Kurohama Shinji Okano Ryohei Akashi Tsuyoshi Yonekura Satoshi Ikeda Koichi Izumikawa Koji Maemura
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
pp.9800-22, (Released:2022-05-31)
参考文献数
26
被引用文献数
5

A 60-year-old Japanese woman was hospitalized for cardiogenic shock 24 days after receiving the second dose of the COVID-19 BNT162b2 vaccine. Impella-CP left ventricular assist device implantation and venoarterial peripheral extracorporeal membranous oxygenation were immediately initiated along with inotropic support and steroid pulse therapy, as an endomyocardial biopsy specimen showed myocarditis. Three weeks later, her cardiac function had recovered, and she was discharged. An immune response associated with the presence of spike protein in cardiac myocytes may be related to myocarditis in the present case because of positive immunostaining for severe acute respiratory syndrome coronavirus 2 spike protein and C4d in the myocardium.

言及状況

外部データベース (DOI)

Twitter (1377 users, 1575 posts, 2489 favorites)

@niken_hunter @NakaSakamoto https://t.co/Us6ERfCyxO
https://t.co/KAfMFzYscH
https://t.co/KAfMFzYscH
@mpc_xetts @arm_band_ @reacharoundu @Johnincarlisle @YouTube Fulminant.. https://t.co/nwv65jQ0cH
@mpc_xetts @arm_band_ @reacharoundu @Johnincarlisle @YouTube Can you demonstrate the duration of the reduced viral load protection you implied in a recent study https://t.co/nwv65jQ0cH
@useless_priest @graeme_0 1/5 Fulminant myo
@lehw1968 @morus123 @MariamAzeb The mechanism isn't understood. An important paper came out last summer: Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination: A Case Report https://t.co/3BdpuA3IxK
Chine Normalizando la Repentinitis, los diostores no sabes su causa, pero con un mínimo de sentido común se entiende que es la kakune. #StoptheShots Agenda 2030 Miss Reef https://t.co/AJZbJfprai https://t.co/rL3lUI39Cw
心筋炎の説明で使った論文「ワクチン接種後24日目の劇症型心筋炎」の写真はこちら。 A ヘマトキシリン・エオジン染色での心筋炎の組織像 C スパイクタンパク陽性=薄い茶色の心筋細胞 https://t.co/Iad6JAg0Tu https://t.co/9WAGqpYSkD
心筋炎からスパイクタンパクが見つかったみたいですね。長崎大学からの報告。 https://t.co/EemTcOTviZ
@blanc0981 Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination: A Case Report Hiroaki Kawano et al https://t.co/HN6O6VSfDf 貴重な症例報告をありがとうございます。先生の論文について大阪大学の宮坂教授がFacebookで批判しています。反論を公開してください
@Grogu33836391 @AnimalMagic13 @DintMentalFloss Ok, more: https://t.co/AHZDEKK8r7 https://t.co/svDEnuzgIJ https://t.co/3A2xvzNmk6 https://t.co/MHtjs2XCKM I still have more.
@g_houle26 @AmalegaFrancois Ah ben! Fulminant myocarditis 24 days after #Covidvaccination: https://t.co/Rywx6TwPe4 Case of a 60-year-old woman. https://t.co/04pHmdeQfl
@g_houle26 @AmalegaFrancois In case of myocarditis after #Covidvaccination one can find SARS-CoV-2 spike protein antibodies in the heart tissue ... https://t.co/Rywx6TwPe4 Cardiac myocytes seem to extress the spike protein with subsequent heart inflammation. The immune system attacks the heart. https://t.co/9vtoWFqy13
長崎大学の症例報告 mRNAワクチンのスパイクタンパクが心筋炎の心臓から見つかる https://t.co/kcvNf5bh8o Google翻訳でも理解できる。 https://t.co/Odb1gYVKLA #三次市 #甲奴町
長崎大学からの症例報告: mRNAワクチンのスパイクタンパクが心筋炎の心臓から見つかる コメ: 当初、コロナワクチンは血中に入って全身を回ることはない、と言われていたよ。 ワクチンのスパイクタンパクそのものが有害 https://t.co/9RhnJQvVJb https://t.co/Jx3D5MbkYs https://t.co/0k1Tj4aBi2
https://t.co/Gog1HrMXJb
心筋炎病変の心筋細胞にS蛋白陽性反応と。 Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination https://t.co/bWzcTldr8D
J-STAGE Articles - Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination https://t.co/Z5zeAj6wU8
60歳、日本人女性、ファイザー2回目接種後24日目。 劇症型心筋炎の綺麗な生検標本だ!心筋細胞にスパイクタンパクも検出できている! 長崎大学、素晴らしいお仕事です! https://t.co/Iad6JAg0Tu https://t.co/vN3th1uysv
https://t.co/66PLMuHNbV https://t.co/LrRlLEiLKa
https://t.co/66PLMuYQdV https://t.co/QbNOhaHW67
Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination: - immune response to spike protein in cardiac myocytes https://t.co/o9qPFfuv3D
Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination: A Case Report https://t.co/N0dFpjQm2g
Read the full report here. https://t.co/QQWbjcFESa
"A 60-year-old Japanese woman was hospitalized for cardiogenic shock 24 days after receiving the second dose of the COVID-19 BNT162b2 vaccine.... [T]he presence of spike protein in cardiac myocytes may be related to myocarditis in the present case." https://t.co/1sH3ekrxXl
@HeyNurseKat @Chrissy60682177 @JohnBoweActor https://t.co/9r1jrj66sH
@VPrasadMDMPH @DenSasja Definitely a relationship to blood factors regulated by ACE2. I’d like to see more molecular biology studies regarding spike protein and effects on ACE2 function. https://t.co/yCURAfp6Pk
@angryhacademic @maureviv @vlher_ @kimisgubbed ^ Average 105 days, spike profile different than controls & LC. Neg multiple past PCRs, anti-nucleocapsid antibody. 24 days: https://t.co/q9O2v61zdd Neg antibody, RT-PCR, antigens, pathogen tests.
@Mhmbread @drclairetaylor I wish that were my understanding, it’s not, and you claim is unsubstantiated wishful thinking at this stage. I respect you acknowledging it is also caused by the current interventions - and this is concerning: https://t.co/gCf2BwYehG Phase 3 > for Tx: https://t.co/75ySL5TQvD
@arrabal81 @VilaniSilva11 Em caso de miocardite após a vacinação covid, pode-se encontrar anticorpos da proteína spike SARS-CoV-2 no tecido cardíaco... Os miócitos cardíacos parecem aumentar a proteína spike com inflamação cardíaca subsequente. O sistema imuno ataca o coração.
60 yaşında Japon kadın, ilk doz vurulduktan 24 gün sonra kardiyojenik şok nedeniyle hastaneye kaldırıldı! Tedavisi 3 hafta sürdü! Sıvılanmaya bağlı Fulminan Miyokardit vakası: https://t.co/Z2h6KHf8fM https://t.co/J9z6iNPpqQ
@Marcucio_Lab @IamBrookJackson https://t.co/C1uFr580LN
@polindromes @jorgeadedo @gransorpresa @Jose_NavarreteV @paeguiguren @OurWorldInData tengo cientos de estudios respaldado por pares que no puedes negar que fueron por la vacuna, no son seguras aunque el porcentaje no sea exorbitantemente alto de casos no significa seguridad https://t.co/opHX3prkfb
@fbozza @borghi_claudio Certo che se annovera https://t.co/nz1ljx47Qy come rivista scientifica allora vale anche Topolino. Riproviamo https://t.co/bg7p3hLPkk https://t.co/D88HimbiV7 https://t.co/gENpou5Il9
@stephanieseneff @stephanieseneff mRNA-induced spike protein found in the heart 24 days post-shot? "positive immunostaining for SARS2 spike protein and C4d in the myocardium." https://t.co/iudJsrXVNU https://t.co/VJCAbOuQOt
@BiologistBunk @Mariejobin1 Example 1: Negative for C-19 antibody, RT-PCR, and antigens as well as for routine pathogen tests. https://t.co/q9O2v5JpZ5 Example 2: All biopsy-confirmed cases tested negative for SARS-CoV-2 using E-gene-specific sequences. https://t.co/F95YzqPqqT
@JesslovesMJK Spike in heart after Pfizer: "immune response associated with the presence of spike protein in cardiac myocytes may be related to myocarditis in the present case because of positive immunostaining for SARS2 spike protein and C4d in the myocardium(May 2022) https://t.co/ONxOAzSpsd https://t.co/lS3so75Shz
Spike in heart after mRNA: "immune response associated with the presence of spike protein in cardiac myocytes may be related to myocarditis in the present case because of positive immunostaining for SARS2 spike protein and C4d in the myocardium."(May 2022) https://t.co/iudJsrGkWm https://t.co/B5NvIC8X3w
@AlKapDC https://t.co/Q54z0kvLdd
@Old_Nash @erikinhamagic @g1paranaoeste #Miocardite fulminante 24 dias após a #VacinaCovid - Caso de uma mulher de 60 anos. https://t.co/ZLMDjgFh72 https://t.co/CL2GcyyhTz
@Old_Nash @erikinhamagic @g1paranaoeste https://t.co/QbDOZcjgop https://t.co/CcyoXG98tJ
@balkraix @RGBDOS @Devils_Iawyer Las fuentes que ocupa y son estas, contexto: el hilo que hizo es para decir que la vacunacion esta causando microcaridits. https://t.co/izqa9A1QvM https://t.co/EEekNOjL9P https://t.co/sHJ4uy60MH https://t.co/NNS8uwalbS https://t.co/7KmOszmJXM https://t.co/Cv6H50yYBO
@benishii_ @ArbiterOfTweets @BrantChil @tegenwindmolen @Beagle_Dirk @stephaniedhose @vrtnws @alaingrootaers @GVDBossche @torfsrik @HarrySpoelstra Spike eiwit na vaccinatie, aangetroffen in het hart bij deze patiënten, volgens @HarrySpoelstra allemaal bs. Iemand die dergelijke observaties afdoet als bullshit is een kwakzalver! https://t.co/NAWkO27Gqv https://t.co/iQvaQYx41H
@gadboit @ColorfulReacti1 @angryhacademic @vlovesp Linking to the Japanese study referenced in the first tweet of the thread for ease of access: https://t.co/MtsrRyI21i
@DrRotunnog https://t.co/h7UDqDIqPQ
Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination: A Case Report https://t.co/HWhIf0M4rt 60 歳の日本人女性、COVID-19 BNT162b2 ワクチンの 2 回目接種後 24 日目に心原性ショックで入院した。心内膜生検で心筋炎を指摘され,直ちにインペラCP
ℹ️Miocarditis fulminant 24 dies després de la vacunació amb àcid ribonucleic missatger de la malaltia del coronavirus: un informe de cas https://t.co/bZGZdCgahi
Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination: A Case Report #PostVac https://t.co/136UIElIH0
@gadboit @juli_bg_bs @angryhacademic @DeansKevin @longvaccvoyager @matthewshaw1111 @cazd45 ..is... this is the first time that someone finds spike in the heart after vax and I understood that it was done about 24days after the jab. https://t.co/PvLv4JS1ky
https://t.co/gwTUI3DOw3
"In caso di miocardite dopo il VACCINO si possono trovare anticorpi della proteina Spike nel tessuto cardiaco. Il sistema immunitario attacca il cuore." https://t.co/4LEAfmpHUn Via consenso_disinformato
Studio clinico: "Miocardite fulminante 24 giorni dopo il VACCINO. Il caso di una donna di 60 anni." AIFA esclude dalle analisi di correlazione con il VACCINO i decessi due settimane dopo la VACCINAZIONE. https://t.co/4LEAfmpHUn Via consenso_disinformato
@Grzegorz_Red https://t.co/yP0pLm7wgS https://t.co/TbCNtPQadE https://t.co/QZ9ymoehed https://t.co/JuQjcN2r6b https://t.co/Yhd9gYH7mE https://t.co/IDE5b62Xd2 https://t.co/lAoISGDrvQ https://t.co/xOoqaxvaDD https://t.co/2guazHwZwJ
"In caso di miocardite dopo il VACClNO si possono trovare anticorpi della proteina Spike nel tessuto cardiaco. I miociti cardiaci sembrano estrinsecare la proteina Spike con conseguente infiammazione del cuore. Il sistema immunitario attacca il cuore." https://t.co/4A02b6bVnH
Studio clinico: "Miocardite fulminante 24 giorni dopo il VACClNO. Il caso di una donna di 60 anni." AIFA esclude dalle analisi di correlazione con il VACClNO i decessi due settimane dopo la VACClNAZlONE. https://t.co/4A02b6bVnH
@orwell2022 not the vector but most likely the spike protein cardiomyocites are expressing the spike the immune system is attacking the heart https://t.co/yCNSOVeGCR.
J-STAGE Articles - Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination: A Case Report https://t.co/aJxObUFPum
#Miocardite fulminante 24 dias após a #VacinaCovid - Caso de uma mulher de 60 anos. https://t.co/rad3pxofPx https://t.co/cplpJomRQq https://t.co/5Pr4KEkwxD
PUBLICACIÓN CIENTÍFICA 34 : en persona muerta por infarto 24 días después de la segunda dosis de la vacuna Covid-19 génica se encontró proteína Espiga de la vacuna en células del corazón, sugiriendo un ataque inmunológico del propio cuerpo al corazón. https://t.co/OztvP9HJoM
"A 60-year-old Japanese woman was hospitalized for cardiogenic shock 24 days after receiving the second dose of the COVID-19 BNT162b2 vaccine" Source: Japanese Society of Internal Medicine https://t.co/E8t0nXM01z
Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination: A Case Report https://t.co/SX1xYvzqjg
https://t.co/tFc0PaaKvq
#usa #covid #vaccine #vaccineforchildren Please do not poison your children Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination: A Case Report https://t.co/mwlE73xvOz
#Covidaşısından 24 gün sonra fulminan miyokardit: https://t.co/6jZ0XirV09 60 yaşında bir kadın vakası... https://t.co/CY9qFmTwoK
#IchooseCOVAXIN #Ocugen #BharatBiotech #IRefusemRNA @billmaher @BraunChelsea https://t.co/RU1xJKd7yX
#IchooseCOVAXIN #Ocugen #BharatBiotech #IRefusemRNA @NikkiFried @RepDWStweets @RepWilson @RepTedDeutch @repLoisFrankel @Sheila4Congress @USRepkCastor @CharlieCrist @repvaldemings @repDarrenSoto @Sheila4Congress @RepStephMurphy @RepAlLawsonJr https://t.co/RU1xJKd7yX
@MarkWarner https://t.co/RU1xJKd7yX
#IchooseCOVAXIN #Ocugen #BharatBiotech #IRefusemRNA @SenatorBurr @RandPaul @SenatorCollins @SenBillCassidy @lisamurkowski @SenatorBraun @RogerMarshallMD @SenatorTimScott @SenatorRomney @TTuberville @JerryMoran @ReverendWarnock @ossoff @Rep_Stansbury https://t.co/RU1xJKd7yX
#IchooseCOVAXIN #Ocugen #BharatBiotech #IRefusemRNA @PattyMurray @SenSanders @SenBobCasey @SenatorBaldwin @ChrisMurphyCT @timkaine @SenatorHassan @SenTinaSmith @SenJackyRosen @SenatorLujan @Hickenlooper https://t.co/RU1xJKd7yX
#IchooseCOVAXIN #Ocugen #BharatBiotech #IRefusemRNA @WPTV @WPBF25News @CBS12 @FOX29WFLX @FOX29WFLX @pbpost @WMBBTV @WCTV @ABC7SWFL @WFTV @News12LI @amanpour https://t.co/RU1xJKd7yX
#IchooseCOVAXIN #Ocugen #BharatBiotech #IRefusemRNA @WPLGLocal10 @nbc6 @SunSentinel @CBSMiami @wsvn @WPTV @miaminewsnow @MiamiNewTimes @pbpost @MiamiHerald @ruth5news @MiamiTodayNews @abc4utah https://t.co/RU1xJKd7yX
#IchooseCOVAXIN #Ocugen #BharatBiotech #IRefusemRNA @NPRHealth @NYTHealth @bbchealth @WSJhealth @USATODAYhealth @Reuters_Health @NBCNewsHealth @KHNews @healthmagazine @KPIXtv @TIMEHealth @DrWeil @CBSHealth @ABonTV @NewsNation @sltrib @huffpost @JacqEHoward https://t.co/RU1xJKd7yX
#IchooseCOVAXIN #Ocugen #BharatBiotech #IRefusemRNA @GovTimWalz @RepDeanPhillips @Ilhan @RepAngieCraig @RepTomEmmer @RepThomasMassie @RandPaul @SenatorWarnock https://t.co/RU1xJKd7yX
#IchooseCOVAXIN #Ocugen #BharatBiotech #IRefusemRNA @SpeakerPelosi @RepSpeier @RepWilson @SenWarren @RepDWStweets @SenSanders @SenSchumer @SenAlexPadilla @SenFeinstein @RandPaul @RepTedDeutch @RepThomasMassie @OccupyDemocrats https://t.co/RU1xJKd7yX
Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination: A Case Report https://t.co/TOKY4tDqnn
⁦@US_FDA⁩ bother to address this? Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination: A Case Report. #IchooseCOVAXIN #investigateFDA https://t.co/PzpL7O1ddT
@Devils_Iawyer https://t.co/4sHEDzpZRb https://t.co/r21Z0k7kBK https://t.co/a0tdYnKoJv
https://t.co/GOnEuu35uS
コロナウイルスワクチン接種24日後の劇症型心筋炎 60歳の日本人女性が,ワクチン2回目接種後24日目に、心原性ショックで入院、心筋炎を指摘された。3週間後に退院。スパイクタンパク質の存在に伴う免疫反応が、心筋炎に関与している可能性がある. https://t.co/bRb7z28cF7
#Covidvaccination 接種後に心筋炎を起こした場合、心臓組織にSARS-CoV-2スパイクタンパク質の抗体が検出されることがあります ... https://t.co/C7ZyOGH9be 心筋細胞は、その後の心臓の炎症に伴い、スパイクタンパク質を抑制するように見えます。免疫系が心臓を攻撃します。 https://t.co/I4kqljVIbb
#Covidvaccination 接種から24日後の劇症型心筋炎: https://t.co/C7ZyOGH9be 60歳女性の症例。 https://t.co/YO00XyUCAN
Résumé : Le système immunitaire attaque le cœur. En cas de myocardite après
如果#Covidvaccinination 後發生心肌炎,可以在心臟組織中找到 SARS-CoV-2 刺突蛋白抗體... https://t.co/O6dZKqf8nW 心肌細胞似乎會在隨後的心臟炎症中表達刺突蛋白。 免疫系統攻擊心臟。 https://t.co/q5UorCPHWw https://t.co/5ouhIfwMMN
Case study: “Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination” https://t.co/N7mVRKJq6n
@ELeonardLiddle @Storiesofinjury An immune response associated with the presence of spike protein in cardiac myocytes may be related to myocarditis, see positive immunostaining for severe acute respiratory syndrome coronavirus 2 spike protein and C4d in the myocardium. https://t.co/HgG2xwtvUJ
In case of myocarditis after #Covidvaccination one can find SARS-CoV-2 spike protein antibodies in the heart tissue ... https://t.co/WhTjvzgPWW Cardiac myocytes seem to extress the spike protein with subsequent heart inflammation. The immune system attacks the heart. https://t.co/wiwUFpeitO
Fulminant myocarditis 24 days after #Covidvaccination: https://t.co/WhTjvzgPWW Case of a 60-year-old woman. https://t.co/xiHhwCyAVP
In case of myocarditis after #Covidvaccination one can find SARS-CoV-2 spike protein antibodies in the heart tissue ... https://t.co/XElf8CICj4 Cardiac myocytes seem to extress the spike protein with subsequent heart inflammation. The immune system attacks the heart. https://t.co/nm97NAMN9f
Myocarditis Fulminant 24 Hari setelah suntikan: Laporan Kasus - Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination: A Case Report https://t.co/i3BRqZehs9
"Myocardite fulminante 24 jours après la vaccination à l'acide ribonucléique messager de la maladie à coronavirus : étude de cas." https://t.co/TKinsTJ4pY
Fulminant myocarditis 24 days after #Covidvaccination: https://t.co/XElf8CICj4 Case of a 60-year-old woman. https://t.co/1L9L4cH8yC

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