著者
吉田 哲 安田 季道 白川 寛夫
出版者
Japanese Association for Acute Medicine
雑誌
日本救急医学会雑誌 (ISSN:0915924X)
巻号頁・発行日
vol.8, no.9, pp.389-394, 1997-09-15 (Released:2009-03-27)
参考文献数
16

We experienced a case of severe systemic hyper-sensitivity reaction with sustained shock and disseminated intravascular coagulation (DIC) following intravenous injection of milk. A 41-year-old nurse injected 150ml of cow's milk into her vein in a suicide attempt. Chills, high fever, nausea and systemic erythema appeared immediately after the injection. On admission, her circulation was severely collapsed, and marked loss of peripheral vascular resistance was demonstrated by Swan-Gantz catheter monitoring. Laboratory data revealed a transient leucopenia with a decrease in the serum level of complement, which was followed by a marked leukocytosis over a week. DIC and hypercalcemia were also observed. The hyperdynamic shock was resistant to therapy during the first 24 hours, but was successfully treated by high doses of methylprednisolone, norepinephrine and fluid resuscitation. DIC could be managed by the administration of nafamostat mesilate and an AT III agent. No fat embolism or bacteremia was observed. The patient was discharged from our hospital without any complication on day 10. It was assumed that the type III allergic reaction to foreign proteins in cow's milk was responsible for the severe systemic reaction observed in our patient.

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牛乳の静脈内注射は1873年のコレラ患者に代用血漿療法とされるも詳細不明。 1996年7月12日に41歳の看護婦が自宅で精神薬を服用し牛乳150mlを自己注射し自殺を試みる。意識朦朧で3時間半後に搬送、10日後に退院。①アレルギー反応②細菌への敗血症③脂肪塞栓④成分の生理活性が https://t.co/fL15heVoLf https://t.co/wT2hIjjAvM
血管に牛乳入れたらどうなんのかなって調べてたら、牛乳150mlを自分に静注したロックな症例出てきた。 https://t.co/NS7vjkWn3c
@tonki_hote https://t.co/ppHmuHZk77
”牛 乳 の静 脈 内投 与 は,1873年 に瀕 死 の コ レラ患 者 に対 す る治 療 法 と して初 め て 試 み られ1),し ば ら く の 間,「 代 用 血 漿 療 法 」として 用 い られ た歴 史 を もつ” https://t.co/Akrnq3PXDb 事実は恐ろしい……

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