著者

Daisuke Nakajima Yusuke Kawashima Osamu Ohara

出版者

Japanese Proteomics Society

雑誌

Journal of Proteome Data and Methods (ISSN:24346454)

巻号頁・発行日

vol.5, pp.8, 2023 (Released:2023-04-29)

参考文献数

4

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To analyse deep protein profiling of dried blood spot (DBS). We developed a simple method using sodium carbonate precipitation (SCP). SCP enriches hydrophobic proteins from DBS, allowing substantial removal of soluble proteins. In combination with SCP, we used quantitative LC-MS/MS proteome analysis in a data-independent acquisition mode (DIA) to enhance the sensitivity and quantification limits of proteome analysis.