著者
高島 響子
出版者
一般社団法人 日本移植学会
雑誌
移植 (ISSN:05787947)
巻号頁・発行日
vol.57, no.1, pp.37-43, 2022 (Released:2022-05-19)
参考文献数
23

Uterus transplantation (UTx) has become a new potential option for women with absolute uterine factor infertility (UFI), who desire to give birth to their own children. In UTx, organ transplantation from living or deceased donors is used under the goal of assisted reproductive technology. In July of 2021, the commission for ethical issues on UTx under the Japanese Association of Medical Sciences published the report, and allowed the conducting of clinical research on UTx with a limited number of patients. This article discusses bioethical considerations of UTx. Transplantation from a living donor is an exceptional procedure which does not fulfill ethical principles of non-maleficence nor justice. Autonomy is also affected because the national guideline requires that a donor should primarily be a family member of the recipient and it raises a concern whether both a donor and a recipient feel pressure. Transplantation from a living donor is accepted because beneficence (saving a patient’s life) surpasses the other principles. This formula cannot be applied to UTx from living donors because the uterus is not a vital organ, and it is difficult to ethically justify such a transplantation. The interest of children is another important ethical issue. From a research ethics perspective, UTx is an unproven intervention to achieve the clinical goal for UFI women. Implementing UTx not as treatment but as clinical research first is supported by the standard of research ethics today. However, allowing clinical research embraces the practice of UTx itself, while unresolved ethical considerations are left behind. Continuous discussion open to public, review of institutional systems including legislation reform, and wholistic care and support for UFI women are needed.

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引用元(PDF) 1枚目: https://t.co/mxaFUTeDYC 2枚目: https://t.co/K0uOA6dEl6
『生命倫理学の立場から見た子宮移植の論点』 https://t.co/wZdAHrZhvp
子宮移植に関して、倫理的な問題が気になっていたのでこちらの論文はその辺りが分かりやすくまとめられていて解像度が上がった フラットな目線で論じられているので反対派、賛成派どちらが読んでも得るものがありそう 生命倫理学の立場から見た子宮移植の論点 - J-Stage https://t.co/rYvcFDbKIR
出生前検査を例に、仮に実施例が積み重なったとしても、必ずしも社会的に受容されたわけではないという意見には同意。 >研究としての実績があることで,技術としてすでに許容されたもの,ELSI(倫理的・法的・社会的論点)が解決したかのように見なされないか懸念される。 https://t.co/K0uOA6dEl6
日本語で読めるものだと、子宮移植の生命倫理学的な課題はこちらの論文にまとまっていそう https://t.co/OUZd5FHmc3

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