著者

齋藤 淑子 内藤 俊夫 久木野 純子 奥村 徹 関谷 栄 礒沼 弘 渡邉 一功 檀原 高 林田 康男

出版者

一般社団法人 日本感染症学会

雑誌

感染症学雑誌 (ISSN:03875911)

巻号頁・発行日

vol.78, no.1, pp.70-75, 2004

被引用文献数

1

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We report a 32-year-old female with eating disorder whose body weight was only 20kg. She was admitted to the hospital with severe low nutrition, low proteinemia, liver dysfunction, hypokalemia and hypoglycemia. On the third hospital day, she had a high fever and <I>Campylobacter fetus</I> subsp. fetus (<I>C. fetus</I>) was isolated from the blood. After treatment with meropenem (1g/day) intravenous drip injection, her condition improved.<BR><I>C. fetus</I> sepsis is not common disease in Japan. A review of 37 cases of this disease in Japan revealed that the age range of adult patients was 20 to 60 years old. The male-to-female ratio was 4.6 to 1.0. Seventy-eight percent of the patients had underlying diseases which were composed of 11 patients with liver disease, 6 patients with blood dyscrasia and some with diabetes mellitus, heart disease, other malignant tumor and collagen disease. There was no case with eating disorder. All apparent sources of infection in Japan originate from eating raw food. Gastrointestinal symptoms were observed in only 16% of the patients. Recent recommendations for the treatment of <I>C. fetus</I> sepsis are to use gentamicin, imipenem and meropenem. Some strains of <I>C. fetus</I> have resistance to erythromycin, ciprofloxacin. The mortality of this infection is 14% in Japan.