- 著者
-
大坪 寛子
小林 正之
酒井 紀
海渡 健
吉田 真弓
島田 貴
増岡 秀一
西脇 嘉一
佐伯 明子
坂本 光男
関田 徹
- 出版者
- 一般社団法人 日本血液学会
- 雑誌
- 臨床血液 (ISSN:04851439)
- 巻号頁・発行日
- vol.37, no.12, pp.1425-1427, 1996
Severe anemia A 37 year-old male with therapy resistant multicentric Castleman's disease (MCD) anemia was treated by subcutaneous injection of erythropoietin. Although immunoglobulin and CRP concentration increased, anemia obviously improved with hemoglobin levels increasing from 4.8 g/d<i>l</i> to 8.5 g/d<i>l</i> without any side effects. Colony assay revealed that the bone marrow mononuclear cells responded to erythropoietin in a dose dependent manner. The mechanism of anemia of MCD is not clearly understood, and treatment is sometimes very difficult. There is no other previous report concerning erythropoietin as a treatment for anemia in MCD.