著者

上原 皓 河本 浩明 今井 壽正 白井 誠 曾根 政富 野田 幸子 佐藤 栄人 服部 信孝 山海 嘉之

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.57, no.6, pp.206-214, 2019-12-10 (Released:2020-02-29)

参考文献数

34

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Gait festination (GF) is one of the representative locomotion disturbances associated with Parkinsonism, which induces pulsion caused by increased stepping velocity. Fear of falling over and involuntary symptoms caused by GF can have a significant impact on quality of life. Considering previous interventional strategies for GF and their utility in daily life, physical intervention using a wearable system to assist postural disorder and the hastening phenomenon is necessary for patients with GF. The purpose of this study was to develop a wearable system that can assist the patient in extending the trunk and generating internal rhythm. Another objective was to confirm the effectiveness of the system for preventing GF by conducting a gait experiment in a Parkinsonism patient. To design an assistive method, we simulated lateral swing in the standing position based on features of Parkinsonism, and defined the mechanism and power configurations for the system. A power unit at the back of the waist transmits a cyclic force to the chest by a link in the frontal plane. A gait experiment was performed in a Parkinsonism patient with GF to confirm that reduction of the gait cycle is prevented by using the system. The result showed that the linear trendline slope of reduction of the gait cycle decreased. In addition, the maximum stooping angle decreased by half, and the cyclic assistance of the system and gait cycle were harmonized. These results suggest that the system developed is effective in preventing GF by supporting posture and generating internal rhythm.

著者

平林 久吾 今井 壽正

出版者

一般社団法人 日本内科学会

雑誌

日本内科学会雑誌 (ISSN:00215384)

巻号頁・発行日

vol.85, no.5, pp.720-724, 1996-05-10

参考文献数

5

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脳幹脳炎は大きく3種類に分類される.すなわちBickerstaff型脳幹脳炎(parainfectiousbrainstem encephalitisを含む),感染性脳幹脳炎(結核性,単純ヘルペス性,日本脳炎など),原因不明の脳幹脳炎(神経Behcet病,飯塚型脳幹脳炎)である.最近の神経科学の進歩に伴ない, Bickerstaff型脳幹脳炎の病因の一部に抗GQlb抗体の関与が明らかとなってきた.感染性脳炎の原因菌やウイルスの同定にELISA法やPCR法が導入され,早期診断,早期治療に役立っている.脳幹脳炎はいまだに原因不明(Bickerstaff型脳幹脳炎の一部も含む)のものが主体をなしており,さらなる原因の究明が待たれる.