著者
大津 光寛 長谷川 功 岡田 智雄 石井 隆資 佐藤 田鶴子
出版者
Japanese Society of Psychosomatic Dentistry
雑誌
日本歯科心身医学会雑誌 (ISSN:09136681)
巻号頁・発行日
vol.16, no.1, pp.67-69, 2001-06-25 (Released:2011-09-20)
参考文献数
5

We report the case of dental treatment for a patient of oral cenesthopathy followed by depression which appears to have been induced by the extraction of a tooth. The significance of the early discovery of depression in patients who require dental treatment and the adequate management of the mental status of such patients are discussed. This case suggests that the dental treatment that fails to take account of latent depression in a patient will not only obstruct improvement of the oral environment but also itself become a factor in making the depression worse.
著者
松野 智宣 北原 和樹 田中 正司 佐藤 田鶴子 荒井 千明
出版者
JAPANESE SOCIETY OF ORAL THERAPEUTICS AND PHARMACOLOGY
雑誌
歯科薬物療法 (ISSN:02881012)
巻号頁・発行日
vol.21, no.2, pp.53-58, 2002-08-01 (Released:2010-06-08)
参考文献数
13
被引用文献数
2

Platelet-rich plasma (PRP), separated by centrifugation of autologous blood, is a plasma containing numerous platelets. Consequently, efficient separation of PRP can provide highly concentrated autologous growth factors, including platelet-derived growth factor (PDGF), transforming growth factor-β (TGF-β), and insulin-like growth factor-I (IGF-I), derived from α granules. However, it requires a substance to trigger platelet aggregation, in order to activate platelets to release the growth factors.In the present study, we investigated a procedure of activating platelets (aggregation) with calcium chloride alone, in the absence of thrombin, the safety of which is suspected. Prior to the investigation, we sought the optimal centrifugal conditions, i.e., centrifugal gravity and time, for separation of PRP. As a result, we discovered that a centrifugal gravity of 130 (×g) and a centrifugal time of 10 min, are the optimal conditions for separating PRP. The time required for platelet aggregation was prolonged in platelet activation by calcium chloride alone, as compared with platelet activation by thrombin. However, activation of platelets with calcium chloride alone demonstrated gelatinization of PRP indicative of sufficient fibrin formation.