著者

堀切 豊 日吉 俊紀 川平 和美 田中 信行 渡邊 智 藤原 敏雄 川崎 義巳

出版者

一般社団法人 日本温泉気候物理医学会

雑誌

日本温泉気候物理医学会雑誌 (ISSN:00290343)

巻号頁・発行日

vol.61, no.2, pp.95-100, 1998 (Released:2010-04-30)

参考文献数

15

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Phthalides and ligustilide in Senkyu extract and limonene and fravonoids in Chimpi extract have been reported to have strong vasodilation effects.In the present study the circulatory effects of Senkyu and Chimpi extract (crude drug extract) were studied as bath agent in 40.0°C bath water (Senkyu ext. 224mg and Chimpi ext. 272mg/2001). Thirteen healthy men (36.2±5.8 years old) took a bath at 40.0°C for 10 min with and without (only with flavor and dye) crude drug extract and the circulatory effects were followed for 30 min after bathing.Heart rate and cardiac output were increased equally by 10 min bathing either with or without crude drug extract. Although systolic blood pressure was slightly increased during bathing, diastolic blood pressure and total peripheral resistance were significantly decreased during and after bathing with and without crude drug extract. Forehead skin blood flow and sublingual temperature were significantly increased during bathing, and remained at higher level for 10-30 min after bathing with crude drug extract. Venous blood pO2 and pH were significantly increased and pCO2 was decreased equally with and without crude drug extract. Plasma NE was significantly increased by bathing with crude drug extract.Bath agent with Senkyu and Chimpi extract are considered favorable as bath agent to keep high skin blood flow and sublingual temperature probably due to its vasodilating effects.

著者

堀切 豊 下堂園 恵 王 小軍 須藤 和彦 林 菊若 田中 信行 小原 該一

出版者

一般社団法人 日本温泉気候物理医学会

雑誌

日本温泉気候物理医学会雑誌 (ISSN:00290343)

巻号頁・発行日

vol.63, no.4, pp.181-186, 2000 (Released:2010-04-30)

参考文献数

12

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The effects of high concentration mineral water bating (31.16g/kg, mainly composed of Na, Ca, Mg chloride and sulfate) were studied in 13 healthy men (44.9±16.3y.o.). The subjects took 41°C, 10min bathing and kept warmth by a blanket for 30min. Blood pressure (BP), Heart rate (HR), cardiac output (CO), total peripheral resistance (TPR) and sublingual temperature by electric thermista as deep body temperature were measured during and after bathing. Skin blood flow by LASER doppler flow meter and venous partial gas pressure and pH were also measured.Sublingual and forehead temperature was increased significantly by +1.4°C after 10min bathing and +0.9°C increase continued even after 30min. Diastolic BP and TPR were significantly decreased, and HR and CO were significantly increased by +20bpm and +2.7l/min, respectively. Significant increase of skin blood flow was also demonstrated. Significant increase of venous pO2 (+20 Torr) and decrease of pCO2 (-8.0 Torr) suggested the improvement of peripheral oxidative metabolism due to increased CO.High concentration mineral water bathing was highly effective than simple water bathing probably due to the thick coating effect by binding concentrated minerals with skin furface protein.