著者

堀切 豊 日吉 俊紀 川平 和美 田中 信行 渡邊 智 藤原 敏雄 川崎 義巳

出版者

一般社団法人 日本温泉気候物理医学会

雑誌

日本温泉気候物理医学会雑誌 (ISSN:00290343)

巻号頁・発行日

vol.61, no.2, pp.95-100, 1998 (Released:2010-04-30)

参考文献数

15

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Phthalides and ligustilide in Senkyu extract and limonene and fravonoids in Chimpi extract have been reported to have strong vasodilation effects.In the present study the circulatory effects of Senkyu and Chimpi extract (crude drug extract) were studied as bath agent in 40.0°C bath water (Senkyu ext. 224mg and Chimpi ext. 272mg/2001). Thirteen healthy men (36.2±5.8 years old) took a bath at 40.0°C for 10 min with and without (only with flavor and dye) crude drug extract and the circulatory effects were followed for 30 min after bathing.Heart rate and cardiac output were increased equally by 10 min bathing either with or without crude drug extract. Although systolic blood pressure was slightly increased during bathing, diastolic blood pressure and total peripheral resistance were significantly decreased during and after bathing with and without crude drug extract. Forehead skin blood flow and sublingual temperature were significantly increased during bathing, and remained at higher level for 10-30 min after bathing with crude drug extract. Venous blood pO2 and pH were significantly increased and pCO2 was decreased equally with and without crude drug extract. Plasma NE was significantly increased by bathing with crude drug extract.Bath agent with Senkyu and Chimpi extract are considered favorable as bath agent to keep high skin blood flow and sublingual temperature probably due to its vasodilating effects.

著者

渡邊 智 今西 宣行 藤原 敏雄 川崎 義巳 大塚 吉則

出版者

一般社団法人 日本温泉気候物理医学会

雑誌

日本温泉気候物理医学会雑誌 (ISSN:00290343)

巻号頁・発行日

vol.61, no.3, pp.135-140, 1998 (Released:2010-08-06)

参考文献数

11

被引用文献数

1

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In this study, we investigated the effect of bathing with cut crude drugs on thermal preservability, water holding capacity, and smoothness of the feel. After immersion with cut crude drugs of 5min at 41°C, the forearm skin core temperature was significantly higher than after plain water bathing. Water sorption-desorption tests on the skin in vivo with cut crude drug extract for the functional assessment of the stratum corneum revealed that the GARENIAE FRUCTUS extract, all of cut crude drugs extract, and FOENICULI FRUCTUS extract are significantly superior to plain water bathing in water holding capacity.Furthermore, an evaluation using a skin model revealed that cut crude drugs have effects significantly superior to that of plain water bathing in increasing the smoothness of the feel. The above results clarified that bathing with cut crude drugs has a stronger effect on thermal preservability and that their extract increases water holding capacity and smoothness of the feel.

著者

渡邊 智 藤原 敏雄 川崎 義巳 大塚 吉則

出版者

日本温泉気候物理医学会

雑誌

日本温泉気候物理医学会雑誌 (ISSN:00290343)

巻号頁・発行日

vol.60, no.4, pp.235-239, 1997-08-01

参考文献数

13

被引用文献数

2

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We investigated the effects of bathing with bath preparation (sodium sulfate, sodium chloride, 30g/200l) on the thermal preservability in healthy volunteers. We also investigated these effects on the antioxidative defense system in patients with vibration syndrome (VS). In these investigations, we measured the activities of erythrocyte superoxide dismutase (SOD). After immersion at 41℃ for 5 min, forearm skin temperature, photoplethysmograph, and transepidermal water loss increased significantly as compared with those after bathing in a plain water. After bathing for 4 weeks at around 40℃ for 10min, activities of erythrocyte SOD increased significantly. These data indicate that bathing with the bath preparation has a stronger effect on thermal preservability in healthy volunteers and activation of the antioxidative defense system in patients with vibration syndrome due to a significant increase in activities of erythrocyte SOD.

著者

川崎 義巳

出版者

社団法人日本化学会

雑誌

化学と教育 (ISSN:03862151)

巻号頁・発行日

vol.38, no.6, pp.640-643, 1990-12-20