著者

堀江 真理子 堀木 ちさと 飯田 俊二 大谷 智司 岡田 基文 平井 健策 大久保 康人

出版者

一般社団法人 日本輸血・細胞治療学会

雑誌

日本輸血学会雑誌 (ISSN:05461448)

巻号頁・発行日

vol.37, no.5, pp.651-655, 1991-11-15 (Released:2010-03-12)

参考文献数

4

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In the United States, the FDA licenses Red Blood Cells Frozen (RBCF) up to 10 years and the AABB (AMERICAN ASSOCIATION OF BLOOD BANKS)'s Standards allow frozen storage of blood for routine transfusion up to 10 years.But in Japan, the storage period of RBCF for routine transfusion allowed is 5 years and that of the thawed, deglycerolized red blood cells (DRBC) is only 12 hours at 4-6°.The quality of RBCF stored for 5 years or 10 years was investigated to extend the storage period of RBCF and DRBC.ATP levels and morphology scores of DRBC stored for 10 years were high as those of DRBC stored for 5 years but 2, 3-DPG levels were slightly low.The hemolysis of DRBC immediately after deglycerolization was low, but increased rapidly with the storage. The result obtained indicated that the quality of the DRBC was maintained in good conditions. We would like to propose to extend the storage period of the RBCF up to 10 years.

著者

大久保 康人

出版者

関西医科大学医学会

雑誌

関西医科大学雑誌 (ISSN:00228400)

巻号頁・発行日

vol.33, no.4, pp.532-565, 1981-12-20 (Released:2013-02-19)

参考文献数

219

被引用文献数

1

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Four hundred and ninety six families with rare blood phenotypes of the ABO, I, P, Rh, Kell, Duffy, Diego and Jr were detected in Japanese Red Cross Blood Centers, and all these blood samples were re-tested and confirmed in Osaka Red Cross Blood Center. Some of them were reconfirmed by Dr. Ruth Sanger, MRC Blood Group Unit in London.These rare bloods, except Fy (a-), Di (b-) and Jr (a-), were recognized mostly by ABO groupings and antibody screenings.Another ninety seven persons with rare bloods were found among the propositi's family members. Consanguinity rate of the Rh11, Rhmod and -D- was 69.2%, and that of the p phenotype 56.5%, the total consanguinity rate being 63.3%.While most of the -D- (including cD-) propositi experi enced abortion or stillbirth, some of the p female propositi did not suffer from such episodes.Most of the i propositi had a congenital cata ract, but recently an i adult free from the disorder was found in Hokkaido. We think the co-occurrence of the i phenotype and congenital cataract to be due to linkage rather than to pleiotropism.Most Jr (a-) female propositi had anti-Jr' in their sera, but none of them had experienced abortion, stillbirth or hemolytic disease of the newborn.

著者

北濱 睦夫 山口 英夫 硲 文雄 大久保 康人

出版者

一般社団法人 日本輸血・細胞治療学会

雑誌

日本輸血学会雑誌 (ISSN:05461448)

巻号頁・発行日

vol.13, no.3, pp.81-91, 1966 (Released:2010-03-12)

参考文献数

37

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A 38-year-old healthy Japanese woman Mrs. N. has as much B and H substances in her saliva as have normal B individuals, but the B antigen in her red cells is very weak and H is undetectable.Her serum contains weak anti-H. It was considered that Mrs. N. 's blood might be called Bh at the phenotypical level; the suffix “h” is intended to indicate a phenotype lacking the H substance.