著者
奥野 祐次
出版者
日本疼痛学会
雑誌
PAIN RESEARCH (ISSN:09158588)
巻号頁・発行日
vol.29, no.4, pp.233-241, 2014-12-10 (Released:2014-12-29)
参考文献数
17
被引用文献数
1 2

Purpose: Neovessels and accompanying nerves are possible sources of pain. Previous work demonstrated that transcatheter arterial micro−emboliza­tion (TAME) for patients with adhesive capsulitis resulted in excellent pain relief. We hypothesized that abnormal neovessels also play an important role in nighttime shoulder pain with other conditions as well as adhesive capsulitis and that TAME can relieve pain.   Material and Methods: TAME using imipenem ⁄ cilastatin sodium as an embolic agent proceeded to seventeen shoulders in sixteen patients, including adhesive capsulitis (n=6), subacromial impingement syndrome (n=7), rotator cuff tear without surgical indication (n=2), stiff shoulder (n=1), and chronic pain post scapula fracture (n=1). All patients had nighttime shoulder pain and previous conservative therapies applied for at least three months and persisted moderate−to−severe pain (Visual Analog Scale > 50 mm) before treatments. Adverse events, changes in Visual Analog Scale scores of night pain, and changes in self reporting sleep quality scores were assessed at 1 week and at 1, 3, and 6 months after the procedure.   Results: Abnormal neovessels were identified in all cases. No major adverse events were related to the procedures. Transcatheter arterial micro− embolization rapidly decreased nighttime pain visual analog scale scores from 72 ± 7 mm to 42 ± 26 mm at 1 week after the procedure, with further improvement at 1, 3 and 6 months (28 ± 22 mm, 19 ± 24 mm, and 16 ± 23 mm respectively). Self reporting sleep quality scores and nighttime pain frequency improved and maintained for 6 months.   Conclusion: Abnormal neovessels were observed in all patients. TAME of this lesion was feasible, effectively relieved unrelenting chronic night shoulder pain.