著者

鈴木 孝明 寺尾 京平 鈴木 博之 新田 祐幹 高尾 英邦 下川 房男 大平 文和 平丸 大介 小寺 秀俊

出版者

一般社団法人 電気学会

雑誌

電気学会論文誌E(センサ・マイクロマシン部門誌) (ISSN:13418939)

巻号頁・発行日

vol.133, no.5, pp.139-146, 2013-05-01 (Released:2013-05-01)

参考文献数

20

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In this study, we propose a simple observation method of the shape and molecular orientation of the chromosomes extracted from cells for a sample-to-analysis system in clinical diagnosis. The proposed technique is composed of total preparation technique such as cell immobilization, chromosomes extraction, stretching, suspension and analysis using a disposable microchip controlled by centrifugal force only. It is experimentally confirmed that the chip having two kinds of microstructures arranged concentrically on a chip immobilizes cells and stretches chromosomes extracted from the immobilized cells.