著者
山隈 優 廣田 誠 小栗 千里 南山 周平 光永 幸代 光藤 健司
出版者
公益社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.66, no.12, pp.610-615, 2020-12-20 (Released:2021-02-22)
参考文献数
30
被引用文献数
1 1

Delanian et al. reported the efficacy of pentoxifylline-tocopherol-clodronate (PENTOCLO) treatment for osteoradionecrosis (ORN) of the mandible in 2011. Spontaneous sequestration and epithelialization of the mandibular lesion are induced by this method. We report a case of osteoradionecrosis of the mandible which responded to treatment with PENTOCLO. A 60-year-old man was referred to our department with persistent mandibular ORN after definitive chemoradiotherapy for oropharyngeal carcinoma (T2N0M0). Periodontitis of the right second molar caused ORN, followed by pathological fracture. PENTOCLO treatment was started following 4-week antibiotic therapy. The sequestrum spontaneously separated with mucosal epithelialization two months after the treatment started. The second molar was removed at 11 months because of its increasing mobility. The extraction socket had epithelized and computed tomography (CT) showed that the pathological fracture had healed. No adverse events occurred during this treatment course. PENTOCLO may be an organpreserving treatment option for ORN of the mandible.
著者
杉山 聡美 岩井 俊憲 吉井 悠 林 雄一郎 上田 潤 佐久間 要 大橋 伸英 小栗 千里 廣田 誠 藤内 祝
出版者
日本口腔診断学会
雑誌
日本口腔診断学会雑誌 (ISSN:09149694)
巻号頁・発行日
vol.30, no.1, pp.52-55, 2017-02-20 (Released:2017-05-23)
参考文献数
25
被引用文献数
1

Sialoliths commonly occur in the submandibular gland, and parotid gland sialoliths, especially parenchymal sialoliths, are rare. As a minimally invasive surgery, we report here endoscopic removal of a parenchymal sialolith of the parotid gland under local anesthesia.A female in her 40s with swelling and pain in the left buccal region was referred to our department for endoscopic removal to avoid extraoral removal after diagnosis of parotid sialolith in another hospital. Computed tomography showed that the parenchymal sialolith of the left parotid gland was 1.7×1.4×1.0 mm in size. The patient underwent endoscopic removal of the sialolith under local anesthesia as minimally invasive surgery. Complete removal was performed and the postoperative course was uneventful without complications such as swelling of the parotid gland.