著者

小坂 光男 山根 基 松本 実 小粥 隆司 中野 匡隆 塚中 敦子 加藤 貴英 大西 範和 Mitsuo KOSAKA Motoi YAMANE Minoru MATSUMOTO Ryuji OGAI Masataka NAKANO Atsuko TSUKANAKA Takahide KATO Norikazu OHNISHI

雑誌

中京大学体育学論叢 = Research journal of physical education Chukyo University (ISSN:02887339)

巻号頁・発行日

vol.46, no.1, pp.1-15, 2004-11-20

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Biological responses due to thermal stimuli were categorized based on the areas of the human body as well as on the modalities of thermal stresses such as icing, cooling and heating applications. These biological responses reported in previous papers were analyzed based on the concepts of Selective Brain Cooling (SBC) and long-term fever range (FR)-mild hyperthermia. Although no thermophysiological problems occurred in the case reports of biological responses induced by SBC, the effects of those induced by cooling of the body trunk and extremities were not so thoroughly evaluated. On the other hand, the idea of long-term fever range (FR)-mild hyperthermia (39.5-41.0℃) proved to be helpful in therapies enhancing the immune defenses against virulent bacterial diseases through the proliferation of Langerhans cells (LCs) and, under these conditions, it might even be beneficially combined with Selective Brain Cooling (SBC) and body heating to enhance human health and physical performance.

著者

小坂 光男 山根 基 加藤 貴英 小粥 隆司 松本 実 塚中 敦子 大西 範和 Mitsuo KOSAKA Motoi YAMANE Takahide KATO Ryuji OGAI Minoru MATSUMOTO Atsuko TSUKANAKA Norikazu OHNISHI

雑誌

中京大学体育学論叢 = Research journal of physical education Chukyo University (ISSN:02887339)

巻号頁・発行日

vol.45, no.2, pp.77-90, 2004-03-31

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Current interest is attracted to the problem on the correlation between physical exercise and heat shock induced protein (HSP 70), especially on the enhanced postischemic myocardial recovery following exercise induction of HSP 70. From the recent papers, the inducible isoform of the 70kDa heat shock protein (HSP) family, HSP 70kDa has been confirmed to protect cells from protein-damaging stressors and has been associated with not only myocardial protection but also recovery of several tissue damages. In the present review article, therefore, the related papers to exercise induced body hyperthermia, muscular damage and HSP 70 family, and their protection and/or recovery mechanism were collected and analyzed from the view-points of biological functions of stress protein HSP 70 family as well as of Granyl-Granyl Acetone (GGA) the HSP inducer.

著者

小坂 光男 山根 基 松本 実 小粥 隆司 中野 匡隆 塚中 敦子 加藤 貴英 大西 範和

出版者

中京大学

雑誌

中京大学体育学論叢 (ISSN:02887339)

巻号頁・発行日

vol.46, no.1, pp.1-15, 2004-11-20

---

Biological responses due to thermal stimuli were categorized based on the areas of the human body as well as on the modalities of thermal stresses such as icing, cooling and heating applications. These biological responses reported in previous papers were analyzed based on the concepts of Selective Brain Cooling (SBC) and long-term fever range (FR)-mild hyperthermia. Although no thermophysiological problems occurred in the case reports of biological responses induced by SBC, the effects of those induced by cooling of the body trunk and extremities were not so thoroughly evaluated. On the other hand, the idea of long-term fever range (FR)-mild hyperthermia (39.5-41.0℃) proved to be helpful in therapies enhancing the immune defenses against virulent bacterial diseases through the proliferation of Langerhans cells (LCs) and, under these conditions, it might even be beneficially combined with Selective Brain Cooling (SBC) and body heating to enhance human health and physical performance.