- 著者
-
志甫谷 渉
- 出版者
- 日本結晶学会
- 雑誌
- 日本結晶学会誌 (ISSN:03694585)
- 巻号頁・発行日
- vol.62, no.3, pp.143-149, 2020-08-31 (Released:2020-09-03)
- 参考文献数
- 10
Endothelin receptors(ETA and ETB)are G-protein-coupled receptors activated by endothelin-1 and are involved in blood pressure regulation. Using the microfocus beamline BL32XU at SPring-8, we determined 8 crystal structures of human ETB receptor, revealing the drug binding modes and receptor activation mechanism.