1 0 0 0 OA 食餌制限を伴う自発走行運動が成長期および成熟期雄ラットの骨に及ぼす影響
- 著者
- 服部 聡士
- 出版者
- 筑波大学 (University of Tsukuba)
- 巻号頁・発行日
- 2014
2013
1 0 0 0 OA 骨格筋ミトコンドリアの品質管理に対するカロリー制限および運動の影響
- 著者
- 服部 聡士 秋本 崇之
- 出版者
- 一般社団法人日本体力医学会
- 雑誌
- 体力科学 (ISSN:0039906X)
- 巻号頁・発行日
- vol.64, no.4, pp.389-396, 2015-08-01 (Released:2015-07-27)
- 参考文献数
- 63
Mitochondria play a central role in energy production but also are the main cellular source of reactive oxygen species (ROS). It is widely believed that aging is related to the accumulation of oxidative molecular damage due to ROS. Aging also induces a decrease in muscle function. Recent studies indicate that caloric restriction and physical exercise suppress the decrease in muscle function though the maintaining quality of mitochondria. This review provides the current understanding of the influence of caloric restriction and exercise on mitochondrial quality control in skeletal muscle.