著者

水野 佑紀 藤森 英治 吉永 淳

出版者

日本微量元素学会

雑誌

Biomedical Research on Trace Elements (ISSN:0916717X)

巻号頁・発行日

vol.28, no.4, pp.154-161, 2018-02-28 (Released:2018-04-10)

参考文献数

9

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Urinary cadmium (Cd) concentration has been used as a biomarker of long-term exposure to this metal in the previous researches. ICP mass spectrometry (ICP-MS) has become a method of choice for measuring urinary Cd concentrations, however, spectral interference from molybdenum oxide (MoO) has to be removed/corrected for accurate analysis. This study evaluated (1) MoO spectral interference in urinary Cd determination by ICP-MS, and (2) the performance of chelate-resin solid phase extraction (SPE) for removal of the interference. Cadmium concentrations in human urine certified reference materials and human urine samples from a male subject were determined by ICP-MS with mathematical MoO interference correction and ICP-MS preceded by SPE, as well as those by electrothermal atomic absorption spectrometry (ETAAS). The sensitivity and accuracy of the determination of urinary Cd was generally satisfactory for all the 3 methods; however, ICP-MS without SPE was found to give a deviated Cd concentrations for urine samples with higher Mo/Cd ratio due to uncertainty in interference correction. It was concluded that ICP-MS with mathematical interference correction is suitable as a routine method for measuring urinary Cd concentrations, but ICP-MS with SPE can be a method of choice for urine with high Mo/Cd ratio and for highly sensitive and accurate urinary Cd analysis.

著者

河野 修 芝 啓一郎 植田 尊善 大田 秀樹 森 英治 加治 浩三 弓削 至

出版者

West-Japanese Society of Orthopedics & Traumatology

雑誌

整形外科と災害外科 (ISSN:00371033)

巻号頁・発行日

vol.53, no.2, pp.291-293, 2004-03-25

参考文献数

2

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Large curves between 50 and 80 degrees progress after skeletal maturity in untrated idiopathic scoliosis. In patients treated surgically for idiopathic scoliosis, curves sometime progress after removal of spinal instrumentation. Twenty-seven patients were evaluated to quantitate curve progression after removal of spinal instrumentation and identify factors leading to curve progression. Curve progressed in nine out of the twenty-seven patients. Curve progression is related to only curve magnitude, and not to correction rate, interval between operation and removal of spinal instrumentation, age, Rissers sign, type of scoliosis (adolescent, juvenile, infantile) , and spinal balance.