著者

小栗 朋子 石橋 由梨 吉永 淳

出版者

一般社団法人 日本環境化学会

雑誌

環境化学 (ISSN:09172408)

巻号頁・発行日

vol.23, no.1, pp.43-47, 2013 (Released:2013-09-25)

参考文献数

26

被引用文献数

2 3

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Total and inorganic arsenic (tAs and iAs) analysis of soils and house dust samples, collected pair-wise from 41 residences of general public in Japan, was carried out to estimate contributions of these non-dietary oral sources to total daily exposure level of iAs, an established human carcinogen. Total As concentration in the samples was determined after mixed acid digestion followed by ICP mass spectrometric (ICPMS) determination. Non-spectroscopic interference arising from residual carbon in the digest was successfully compensated by addition of 3% acetic acid to sample digest and standard solution. Concentration of iAs in soil and house dust samples (n=20 each) was measured by liquid chromatography- ICPMS after extraction with synthetic gastric juice. Median tAs concentration in soil (n=38) and house dust (n=40) was 10 and 2.5 mg/kg, respectively. Median iAs (AsIII+AsV) concentration was <0.01 and 0.24 mg/kg, respectively. Assuming that adult unintentionally ingest 50 mg each of soil and house dust, daily exposure level was estimated to be 0.0005 and 0.012 μg/day, respectively. When recently reported daily dietary iAs intake (mean of two estimates: 15.4 μg/day) is considered, contributions from soil and house dust to total daily oral exposure was estimated to be 0.003 and 0.08%, respectively. Soil and house dust ingestion, as well as inhalation exposure (estimated to be 0.02 μg/day), was found to be insignificant for total daily iAs exposure of Japanese.

著者

小栗 朋子 吉永 淳

出版者

日本衛生学会

雑誌

日本衛生学雑誌 (ISSN:00215082)

巻号頁・発行日

vol.69, no.3, pp.177-186, 2014

被引用文献数

8

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Objective: The objective was to estimate the inorganic arsenic (iAs) intake of the general Japanese adult population by a probabilistic approach. Methods: Bioaccessible iAs concentrations in rice (n=56) and hijiki (n=32), the two food items that are the major iAs sources for the Japanese, were measured by liquid chromatography-ICP mass spectrometry. The concentration in cooked rice was estimated from the measured concentration in a raw rice sample while taking into consideration the loss of iAs during cooking. The iAs concentration in hijiki was measured using soaked hijiki samples. The daily consumption of cooked rice and soaked hijiki was taken from published data. The distribution profile of daily iAs intake was estimated by multiplying the bioaccesible iAs concentration in cooked rice and soaked hijiki samples by the amount of these samples consumed daily, which were randomly extracted according to the respective distributions. This process was repeated 10,000 times. Results: The distribution profiles of iAs concentration in rice and hijiki were normal and log-normal, respectively, and those of the amount of cooked rice and soaked hijiki consumed were beta and log-normal, respectively. The daily bioaccessible iAs intake values were estimated to be 19 and 59 μg/day at 50 and 95 percentile. At 50 percentile iAs intake, the contributions from rice and hijiki were estimated to be equal, whereas the contribution from hijiki increased with the estimated total daily iAs intake. Conclusions: The iAs intakes of Japanese subjects estimated in previous duplicated portion studies were fairly consistent with the present estimation. Moreover, it was confirmed that the cancer risk derived from dietary iAs intake of the general Japanese population was not negligible.

著者

佐藤 孝雄 巌谷 勝正 長瀬 忍 森 茂樹 能城 修一 吉永 淳 米田 穣

出版者

日本人類学会

雑誌

Anthropological Science (Japanese Series) (ISSN:13443992)

巻号頁・発行日

vol.127, no.1, pp.15-23, 2019

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<p>東京都目黒区祐天寺に所在する阿弥陀堂は,五代将軍徳川綱吉・八代将軍徳川吉宗の養女であった竹姫が,1724(享保九)年,厄除けの為に造営・寄進した堂宇と伝えられる。寺録にはその由来と合わせ,寄進時,施主竹姫の御髪を収めた石箱が須弥壇の下に埋設されたことも記されている。2014年,改修工事のため阿弥陀堂が一時移設されたところ,寺録に記されている通り,須弥壇の真下に当たる位置に基壇に埋設された石箱が現れ,その内部から頭髪と板材片,白色の粉塊,懐中鏡ほか若干の遺物を発見するに至った。小稿では,それらの観察所見・分析結果を報告し,将軍家養女の中でもひときわ著名な竹姫の食性と厄除け行為について推測し得た事柄を記す。</p>

著者

高岡 路枝 吉永 淳 田中 敦

出版者

一般社団法人 日本環境化学会

雑誌

環境化学 (ISSN:09172408)

巻号頁・発行日

vol.17, no.4, pp.629-634, 2007-12-18 (Released:2008-10-24)

参考文献数

12

被引用文献数

2 1

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The concentrations of heavy metals (V, Mn, Co, Cu, Zn, Cd, Ba, in addition to Pb which was reported elsewhere) in surface soil samples collected from 31 public playgrounds in a ward in Tokyo were determined by ICP mass spectrometry after HNO3/HF/HClO4 digestion. Mean concentrations of all metals but Ba exceeded the levels of uncontaminated soils in Japan reported in the previous literature indicating the presence of soil pollution. The exposure to V via direct soil ingestion was estimated to contribute more than that via dietary intake; however, it was not serious enough to warrant immediate attention. For other metals, dietary exposure accounted much more than soil ingestion. There were strong positive correlations between metal concentrations in the soil samples, particularly between V and Mn (r=0.97), V and Co (r=0.95), Pb and Cu (r=0.75), or Pb and Zn (r=0.84). These correlations suggested that the metals, to a certain extent, shared common pollution source.

著者

小栗 朋子 片岡 修治 鈴木 剛 吉永 淳

出版者

一般社団法人 日本環境化学会

雑誌

環境化学 (ISSN:09172408)

巻号頁・発行日

vol.27, no.1, pp.9-15, 2016-12-15 (Released:2017-09-27)

参考文献数

33

被引用文献数

1

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Lead is a neurotoxin and it has a significant adverse effect on the neurobehavioral development of children due to a low-level exposure. In order to see if lead-containing household products are present in the indoor environment in Japan, various products (n=250) were analyzed for total lead concentration with an X-ray fluorescence spectrometry. Lead was detected in 18 of 250 samples at the concentration 0.019 to 14%. It was found that lead was contained in paints and polyvinyl chloride (PVC) covering of the products. Two samples with painted surface had concentrations of lead exceeding 0.06% in the paint, the regulatory limit set by the Japan Paint Manufacturers Association. Eight samples with PVC covering (e.g. extension cord, supply cable) had more lead concentrations than the tolerable maximum concentration value of the RoHS directive in 2006 (0.1%). These products were produced outside Japan, or produced before execution of the RoHS directive. Bioaccessibility of lead in the products was relatively low, ranging from 0.43 to 4.6%. Daily bioaccessible lead intake of a child via the ingestion of fragments of such products was estimated to range from 0.21 to 90 µg/day, and total daily bioaccessible lead intake including contributions from other media (e.g. diet and soil) was estimated to be 4.7 to 94 µg/day. Blood lead concentration of a child, who ingests this amount of bioaccessible lead, was estimated to be 0.75 to 15 µg/dL based on a model formula of the EPA. The result suggested that products with extremely high lead concentration can pose health risk to children via the ingestion of house dust contaminated with fragments of surface covering of such products.

著者

米田 穣 吉田 邦夫 吉永 淳 森田 昌敏 赤澤 威

出版者

Japan Association for Quaternary Research

雑誌

第四紀研究 (ISSN:04182642)

巻号頁・発行日

vol.35, no.4, pp.293-303, 1996-10-31 (Released:2009-08-21)

参考文献数

49

被引用文献数

14 16

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本研究は,縄文時代中期(4,000年前頃)から江戸時代(250年前頃)にわたる8遺跡から出土した人骨38個体を試料として,骨コラーゲンの炭素・窒素同位体分析および骨無機質における微量元素分析を行い,その結果に基づいて長野県における約4,000年間におよぶ食性の時代変遷を検討したものである.結果として第1に,同位体分析から,当地域では縄文時代中期から江戸時代に至るまで主食は基本的にC3植物であったと考えられる.縄文時代から中世にかけては,非常に強くC3植物に依存していたのに対し,江戸時代には海産物の利用の可能性が示唆された.内陸部で庶民の日常食として重要だったと論じられている雑穀類に関しては,今回の分析試料ではC4植物である雑穀を主食とした個体は検出されなかった.また,炭素同位体比から縄文時代北村遺跡出土人骨17個体について食性に性差の存在する可能性が示唆された.第2に,北村縄文人骨1個体で実施した微量元素分析からは,同位体分析で示唆されたC3植物食の内容がシイ・クリを中心とする可能性が示唆された.

著者

本橋 準 吉永 淳

出版者

一般社団法人 電気設備学会

雑誌

電気設備学会誌 (ISSN:09100350)

巻号頁・発行日

vol.29, no.6, pp.402-405, 2009-06-10 (Released:2014-11-12)

著者

水野 佑紀 藤森 英治 吉永 淳

出版者

日本微量元素学会

雑誌

Biomedical Research on Trace Elements (ISSN:0916717X)

巻号頁・発行日

vol.28, no.4, pp.154-161, 2018-02-28 (Released:2018-04-10)

参考文献数

9

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Urinary cadmium (Cd) concentration has been used as a biomarker of long-term exposure to this metal in the previous researches. ICP mass spectrometry (ICP-MS) has become a method of choice for measuring urinary Cd concentrations, however, spectral interference from molybdenum oxide (MoO) has to be removed/corrected for accurate analysis. This study evaluated (1) MoO spectral interference in urinary Cd determination by ICP-MS, and (2) the performance of chelate-resin solid phase extraction (SPE) for removal of the interference. Cadmium concentrations in human urine certified reference materials and human urine samples from a male subject were determined by ICP-MS with mathematical MoO interference correction and ICP-MS preceded by SPE, as well as those by electrothermal atomic absorption spectrometry (ETAAS). The sensitivity and accuracy of the determination of urinary Cd was generally satisfactory for all the 3 methods; however, ICP-MS without SPE was found to give a deviated Cd concentrations for urine samples with higher Mo/Cd ratio due to uncertainty in interference correction. It was concluded that ICP-MS with mathematical interference correction is suitable as a routine method for measuring urinary Cd concentrations, but ICP-MS with SPE can be a method of choice for urine with high Mo/Cd ratio and for highly sensitive and accurate urinary Cd analysis.

著者

藤巻 可弓 荒川 千夏子 吉永 淳 渡辺 知保 芹澤 滋子 今井 秀樹 白石 寛明 水本 賀文

出版者

日本衛生学会

雑誌

日本衛生学雑誌 (ISSN:00215082)

巻号頁・発行日

vol.59, no.4, pp.403-408, 2004-11-15 (Released:2009-02-17)

参考文献数

14

被引用文献数

14 21

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Objective: The daily bisphenol A (BPA) intake level of Japanese pregnant women was surveyed based on the measurement of the urinary excretion level of a BPA metabolite.Methods: Spot urine samples were collected from 56 pregnant women who visited the gynecology division of a hospital for a routine health check between June and October 2003. The urinary concentrations of the BPA metabolite and creatinine were measured by GC/MS/MS and spectrophotometry, respectively. Daily BPA intake was assumed to be equal to daily excretion.Results: The daily intake of BPA among Japanese pregnant women was estimated to be in the range of <0.3 to 7.9μg/day (median<2.0μg/day), being consistent with the levels in previous studies for non-pregnant Japanese women. This level was far below the current Acceptable Daily Intake (0.01mg/kg/day) which was set by the European Commission. The maximum estimated intake per body weight (0.16μg/kg/day) reached 1/10 of the Lowest Adverse Effect Level of BPA for pregnant mice for a reproductive effect on the offspring (2μg/kg/day).Conclusion: It is desirable to lessen BPA intake from a precautionary viewpoint, particularly in pregnant women.

著者

小栗 朋子 吉永 淳

出版者

日本衛生学会

雑誌

日本衛生学雑誌 (ISSN:00215082)

巻号頁・発行日

vol.69, no.3, pp.177-186, 2014 (Released:2014-09-24)

参考文献数

33

被引用文献数

8

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Objective: The objective was to estimate the inorganic arsenic (iAs) intake of the general Japanese adult population by a probabilistic approach. Methods: Bioaccessible iAs concentrations in rice (n=56) and hijiki (n=32), the two food items that are the major iAs sources for the Japanese, were measured by liquid chromatography-ICP mass spectrometry. The concentration in cooked rice was estimated from the measured concentration in a raw rice sample while taking into consideration the loss of iAs during cooking. The iAs concentration in hijiki was measured using soaked hijiki samples. The daily consumption of cooked rice and soaked hijiki was taken from published data. The distribution profile of daily iAs intake was estimated by multiplying the bioaccesible iAs concentration in cooked rice and soaked hijiki samples by the amount of these samples consumed daily, which were randomly extracted according to the respective distributions. This process was repeated 10,000 times. Results: The distribution profiles of iAs concentration in rice and hijiki were normal and log-normal, respectively, and those of the amount of cooked rice and soaked hijiki consumed were beta and log-normal, respectively. The daily bioaccessible iAs intake values were estimated to be 19 and 59 μg/day at 50 and 95 percentile. At 50 percentile iAs intake, the contributions from rice and hijiki were estimated to be equal, whereas the contribution from hijiki increased with the estimated total daily iAs intake. Conclusions: The iAs intakes of Japanese subjects estimated in previous duplicated portion studies were fairly consistent with the present estimation. Moreover, it was confirmed that the cancer risk derived from dietary iAs intake of the general Japanese population was not negligible.