著者

金子 正勝 清水 文治

出版者

The Pharmaceutical Society of Japan

雑誌

Chemical and Pharmaceutical Bulletin (ISSN:00092363)

巻号頁・発行日

vol.20, no.5, pp.1050-1053, 1972-05-25 (Released:2008-03-31)

被引用文献数

3 7

著者

西村 卓三 清水 文治 岩井 一成

出版者

The Pharmaceutical Society of Japan

雑誌

Chemical and Pharmaceutical Bulletin (ISSN:00092363)

巻号頁・発行日

vol.11, no.11, pp.1470-1472, 1963-11-25 (Released:2008-03-31)

被引用文献数

35 55

著者

金子 正勝 清水 文治

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.37, no.1, pp.40-56, 1979-01-01 (Released:2009-11-13)

参考文献数

120

被引用文献数

1 3

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Synthetic procedures of arabinofuranosyl nucleosides, especially, of arabinofuranosyl purine nucleosides are reviewed from the following points of view; i) methods which include nucleoside epoxide as an intermediate ii) direct condensation methods of arabinose derivatives and various purine bases iii) methods which include purine-8-cyclonucleosides as an intermediate and iv) other methods. Biological activities of arabinofuranosyl purine nucleosides are also summarized briefly.

著者

金子 正勝 木村 美佐子 清水 文治 矢野 純一 池原 森男

出版者

The Pharmaceutical Society of Japan

雑誌

Chemical and Pharmaceutical Bulletin (ISSN:00092363)

巻号頁・発行日

vol.25, no.8, pp.1892-1898, 1977-08-25 (Released:2008-03-31)

被引用文献数

2 2

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9-(β-D-Arabinofuranosyl) adenine 5'-phosphate was obtained from adenosine 5'-phosphate via the novel intermediate 8, 2'-O-cycloadenosine 5'-phosphate. In contrast to the synthesis of 9-(β-D-arabinofuranosyl) adenine, it was difficult to cleave this compound by hydrogen sulfide directly to 8, 2'-O-cycloadenosine 5'-phosphate because of a considerable degree of dephosphorylation. However N-acylated 8, 2'-O-cycloadenosine 5'-phosphate was readily cleaved at the cyclo-bond by hydrogen sulfide. Desulfurization of 8-mercapto-9-(β-D-arabinofuranosyl) adenine 5'-phosphate gave the desired pure crystalline product.'