著者

佐野 梓 末次 王卓 秦 晃二郎 柊迫 美咲 片山 美幸 田中 瑠美 田島 壮一郎 グリム 理恵子 辻 敏和 渡邊 裕之 金谷 朗子 増田 智先

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.44, no.5, pp.229-235, 2018-05-10 (Released:2019-05-10)

参考文献数

16

被引用文献数

4

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We have disclosed 14 standardized laboratory data on out-of-hospital prescriptions since June 2015. In this study, we analyzed questions on out-of-hospital prescriptions related to laboratory data over 2 years. There were 229 prescription questions related to laboratory data (3.4% of the total prescription questions), and 79.5% of these were related to renal function. Among renal function-associated laboratory data, serum creatinine was used in most cases. The rate of prescription change after prescription questions was 66.5% for laboratory data associated with renal function, which was significantly higher (P < 0.001) than the 25.5% for other types of data. Furthermore, the clear description of dose reduction requirements on a package insert was confirmed to be one of the common factors for renal excretory drugs. Therefore, it is important to provide renal function laboratory data to facilitate the appropriate adjustment of out-of-hospital prescription doses. In addition, to enable appropriate dose adjustments using laboratory data, the description on the drug package insert should make it easy for pharmacists who are auditing prescriptions to make appropriate judgments.