著者

真柴 裕人

出版者

一般社団法人 日本不整脈心電学会

雑誌

心電図 (ISSN:02851660)

巻号頁・発行日

vol.4, no.2, pp.198-201, 1984-03-01 (Released:2010-09-09)

参考文献数

3

著者

中村 展招 真柴 裕人

出版者

医学書院

巻号頁・発行日

pp.36-37, 1979-01-10

---

はじめに 臨床上,古くからカテコラミン分泌腫瘍である褐色細胞腫,脳血管障害,とくにクモ膜下出血発作時,急性膵炎・胆石症発作時,あるいは体外的にカテコラミン(以下CA)過剰投与を行った際に心電図異常(とくにST.T波の変化)を多く認めてきた.これらの疾患時.体液性あるいは交感神経終末部を介して分泌されるCAが過剰に心筋に作用する場合,またはCAに対する感受性が増大したとき,CAにより心筋が障害を受ける,このように,続発性心筋症の中でCAにより心筋障害をきたした場合をカテコラミン心筋症(catecholaminecardiopathy)1,2)という.

著者

伊東 盛夫 有田 真 佐伯 和之 田上 三雄 福島 勇 矢永 尚士 真柴 裕人

出版者

THE PHYSIOLOGICAL SOCIETY OF JAPAN

雑誌

The Japanese Journal of Physiology (ISSN:0021521X)

巻号頁・発行日

vol.17, no.2, pp.174-189, 1967-04-15 (Released:2011-06-07)

参考文献数

35

被引用文献数

39 46

---

The sequence of spread of sinus node impulse to the venae cavae and the mechanisms of delay at the sinocaval junctional areas were studied with the microelectrode methods.The impulse from the pacemaker located in the sinus node spreads slowly in the nodal tissues (1-10cm/sec) and excites the crista terminalis. Spread is rapid in the crista (50-120cm/sec). Then the impulse spreads from theupper and lower ends of the crista through the sinocaval junctional areas (SC areas) to the right and left superior venae cavae. Conduction velocity is decreased in the SC areas (10-25cm/sec) and again increased in the superior venae cavae (40-80cm/sec). In the inferior vena cava, the conduction of impulse is always completely blocked in the vicinty of the ostium.The features of superior vena caval action potentials are closely similar to those of cardiac action potentials, showing the constant diastolic level, the rapid upstroke, the high amplitude, the clear plateau and the rapid conduction.The fibers in the SC areas apparently show a transitional stage from the nodal fibers to the superior vena caval fibers. The action potentials of the SC areas are intermediate in the amplitude and rate of rise between those of sinus nodal and superior vena caval action potentials, and often reveal a step on the upstroke. The activation of right atrium at high rate produced a delay and block localized to the SC areas. The action potentials of the SC areas show three different types of changes associated with the increased atrial rate: I) the decrease in the amplitude and rate of rise, II) the separation into two discrete spikes and III) the widening of the step-like prepotential.Several evidences were presented which suggest that the SC areas are the latent pacemakers.