著者

北野 菜奈 福本 真一郎 徳山 桂理 池田 恵子 髙橋 俊彦

出版者

日本家畜臨床学会 ・ 大動物臨床研究会・九州沖縄産業動物臨床研究会

雑誌

産業動物臨床医学雑誌 (ISSN:1884684X)

巻号頁・発行日

vol.9, no.1, pp.1-6, 2018-06-30 (Released:2019-05-09)

参考文献数

30

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プアオン式イベルメクチン製剤は公共牧場において長期間継続的に使用されており,消化管内線虫駆虫に有効である.本研究では,駆虫を行っていない牧場を用いて駆虫計画を立案し,対象農場に適した駆虫のタイミングを模索するために,イベルメクチン製剤による駆虫を実施した. 駆虫は試験区にのみ5 月,7 月,10 月に行った.消化管内線虫卵数において試験区が対照区と比較し6 月と8 月で有意に低値を示し,試験区において7 月と比較し8 月,10 月が有意に低値であったこと,体重において試験区で7 月と比較し駆虫後の8 月が有意に増体したこと,繁殖成績でも試験区が良好な傾向を示したことは,イベルメクチン製剤による駆虫から得られた効果であると考えられた. イベルメクチン製剤は世界的に牛で薬剤耐性が報告されている.今回のような投与回数を必要最小限に抑えた駆虫プログラムであれば薬剤耐性は容易に起こらないと思われた.

著者

髙橋 俊彦 夏井 美聡 岸田 美月 北野 菜奈 井上 誠司 菊 佳男

出版者

酪農学園大学

雑誌

酪農学園大学紀要. 自然科学編 (ISSN:21870500)

巻号頁・発行日

vol.47, no.1, pp.1-6, 2022-10

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During the suckling period, calves are prone to physiological anemia. Anemic calves often develop respiratory and digestive problems that lead to poor growth. As a precursor of hemoglobin, aminolevulinic acid has an oxygencarrying function in red blood cells in the body, and is expected to prevent anemia. In this study, we examined the effects of feeding aminolevulinic acid to calves on their growth and analyzed whether it had anemia-preventing effects. Our subject calves were six suckling calves, three of which were orally administered an aminolevulinic acid preparation (5 g/day for 60 days; test group), and three of which received no aminolevulinic acid (controls). At 0, 1, and 3 months of age, body weight, height, daily gain, and blood parameters (red blood cell count, hemoglobin, iron, hematocrit, white blood cell count, total protein, and total cholesterol) were measured, and the number of respiratory and digestive diseases and number of days of treatment were investigated. In the test group, body height was significantly higher at 1 month of age, and daily body mass also tended to be higher at 1-3 months of age. In blood tests, the red blood cell count and hemoglobin were below standard values at birth and at 2 months of age in both the test and control groups. Iron and total cholesterol tended to be higher in the test group at 1 and 3 months of age, while white blood cell count and total protein tended to be higher in the control group. In terms of disease status, the number of days of treatment was small in the test group, and no calves were diagnosed with anemia. These results suggest that aminolevulinic acid may improve the nutritional status of calves and be effective in promoting growth and preventing anemia.