- 著者
- Yukihiro Hashimoto Tsunenari Soeda Ayako Seno Satoshi Okayama Nozomi Fukuda Hiroki Yano Atsushi Iwai Kazutaka Nogi Kaeko Hirai Hajime Fujimoto Megumi Suzuki Hajime Iwama Takehito Nakai Naofumi Doi Yoshihiko Saito
- 出版者
- The Japanese Circulation Society
- 雑誌
- Circulation Journal (ISSN:13469843)
- 巻号頁・発行日
- vol.86, no.12, pp.1968-1979, 2022-11-25 (Released:2022-11-25)
- 参考文献数
- 25
- 被引用文献数
- 1 2
Background: Non-contrast T1 hypointense infarct cores (ICs) within infarcted myocardium detected using cardiac magnetic resonance imaging (CMR) T1 mapping may help assess the severity of left ventricular (LV) injury. However, because the relationship of ICs with chronic LV reverse remodeling (LVRR) is unknown, this study aimed to clarify it.Methods and Results: We enrolled patients with reperfused AMI who underwent baseline CMR on day-7 post-primary percutaneous coronary intervention (n=109) and 12-month follow-up CMR (n=94). Correlations between ICs and chronic LVRR (end-systolic volume decrease ≥15% at 12-month follow-up from baseline CMR) were investigated. We detected 52 (47.7%) ICs on baseline CMR by non-contrast-T1 mapping. LVRR was found in 52.1% of patients with reperfused AMI at 12-month follow-up. Patients with ICs demonstrated higher peak creatine kinase levels, higher B-type natriuretic peptide levels at discharge, lower LV ejection fraction at discharge, and lower incidence of LVRR than those without ICs (26.5% vs. 73.3%, P<0.001) at follow-up. Multivariate logistic regression analysis showed that the presence of ICs was an independent and the strongest negative predictor for LVRR at 12-month follow-up (hazard ratio: 0.087, 95% confidence interval: 0.017–0.459, P=0.004). Peak creatine kinase levels, native T1 values at myocardial edema, and myocardial salvaged indices also correlated with ICs.Conclusions: ICs detected by non-contrast-T1 mapping with 3.0-T CMR were an independent negative predictor of LVRR in patients with reperfused AMI.
- 著者
- Linda MARUSIC Atsushi IWAI
- 出版者
- The Society of Socio-Informatics
- 雑誌
- Journal of Socio-Informatics (ISSN:18829171)
- 巻号頁・発行日
- vol.2, no.1, pp.53-68, 2009-09-30 (Released:2017-02-04)
In this paper we present the problems in developing the learning environment of Japanese as a foreign language in a small European country with its own language, and suggest a method of improvement. The Republic of Slovenia, an EU member state with a population of approximately 2 million, geographically and culturally distant from Japan, is taken as an example. Not only is the number of Japanologists in Slovenia quite small, the small number of potential purchasers results in higher prices for books, leading to difficulties in publishing Japanese language related materials. In this paper, construction of a learning support environment based on an information system incorporating Web 2.0 elements is proposed as the means of improvement: centralizing the existing resources on a single, academically credible website based on the Slovene language and focused on Japanese language learning, and inviting participation from not only Slovene students and scholars, but also Japanese students willing to support foreign students in learning the Japanese language.