著者

Huiqiu Zheng Yanling Wang Bo Yang Jing Wu Yonggang Qian Wenrui Wang Xuemei Wang

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

vol.33, no.11, pp.547-555, 2023-11-05 (Released:2023-11-05)

参考文献数

78

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Background: Hypertension is one of the most common chronic diseases, and dietary factors play an important role in hypertension. We examined the interaction of dietary sodium-to-potassium (Na/K) ratio and dinner energy ratio on hypertension.Methods: We conducted this study using data from the cross-sectional National Survey for Nutrition and Adult Chronic Disease in 2015 in Inner Mongolia, China. Dietary data were collected using 24-hour diet records with food weights across 3 consecutive days. Logistic regression was used to determine the interaction of dinner energy ratio and dietary Na/K ratio on hypertension.Results: A total of 1,861 participants were included in this study, and 914 individuals were hypertensive (49.1%). Dinner energy ratio and high dietary Na/K ratio were independently related to high prevalence of hypertension. A formal test showed that dinner energy ratio interacted significantly with dietary Na/K ratio on hypertension (P < 0.001), with an adjusted odds ratio (OR) of 1.119 (95% confidence interval [CI], 1.040–1.203). Participants whose dinner energy ratio greater than 39.1% and dietary Na/K ratio of 3.625–6.053 had the highest OR of hypertension prevalence, with an adjusted OR of 2.984 (95% CI, 1.758–5.066), compared with participants with dinner energy ratio of 30.2–39.1%, and dietary Na/K ratio less than 2.348.Conclusion: Our study highlighted the interactive effect of dinner energy ratio and dietary Na/K ratio on hypertension among adults in Inner Mongolia. We advocated a balanced diet (dinner energy ratio not small or large) and a low dietary Na/K ratio for reducing the prevalence of hypertension.

著者

Wei Zhang Yingying Wang Xiang Dong Bo Yang Hongyuan Zhou Lu Chen Zewu Zhang Qin Zhang Guangtai Cao Zhiqiang Han Huikai Li Yunlong Cui Qiang Wu Ti Zhang Tianqiang Song Qiang Li

出版者

International Research and Cooperation Association for Bio & Socio-Sciences Advancement

雑誌

BioScience Trends (ISSN:18817815)

巻号頁・発行日

pp.2021.01517, (Released:2021-12-09)

参考文献数

38

被引用文献数

10

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We explored the prognostic value of preoperative CA19-9 in α-fetoprotein (AFP)-positive and -negative HCC with hepatitis B virus (HBV) background (HBV-HCC), and explored the underlying mechanism. Recurrence-free survival (RFS) and overall survival (OS) were assessed in HBV-HCC patients who underwent curative resection (Cohort 1). Immunohistochemical staining of CA19-9 in HCC and liver parenchyma were quantified in another cohort of 216 patients with resected HCC (Cohort 2). Immunohistochemical staining of CA19-9 and serum CA19-9 level was also compared between patients with HCC and intrahepatic cholangiocarcinoma (ICC) (Cohort 3). In Cohort 1, CA19-9 ≥ 39 U/mL was an independent risk factor for RFS (HR = 1.507, 95% CI = 1.087-2.091, p = 0.014) and OS (HR = 1.646, 95% CI = 1.146-2.366, p = 0.007). CA19-9 ≥ 39 U/mL was also associated with significantly higher incidence of macrovascular invasion (MaVI) compared with CA19-9 < 39 U/mL (23.0% vs. 7.2%, p = 0.002), and elevated aminotransferase and aspartate aminotransferase to platelet ratio index (APRI), and lower albumin. Immunohistochemical staining of CA19-9 revealed that CA19-9 expression was found exclusively in the background liver but not in HCC tumor cells. In contrast, tumor tissue was the main source of CA19-9 in ICC patients. CA19-9 ≥ 39 U/mL was associated with worse OS and RFS in both AFP-positive and negative HCC patients. CA19-9 indicated more severe inflammation and cirrhosis in the liver of HCC patients.

著者

Shohei TAKAOKA Tsutomu KAIZUKA Bo YANG Kimihiko NAKANO

出版者

The Japan Society of Mechanical Engineers

雑誌

Mechanical Engineering Journal (ISSN:21879745)

巻号頁・発行日

vol.7, no.2, pp.19-00572, 2020 (Released:2020-04-15)

参考文献数

28

被引用文献数

1

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Methods for presenting information by utilizing a visual field (such as driver peripheral vision) are attracting increased attention in association with an increase in the amount of information required for driver assistance. However, studies on interfaces utilizing such a visual field are currently insufficient. In addition, to avoid information overload, it is important to evaluate different interfaces in terms of the amount of information presented. The authors researched those interfaces from the viewpoint of ergonomics with the purpose that the result is possible to be applied to various researches mainly in the field of automobiles. Through an in-house experiment, participants viewed video clips presenting dot patterns within their peripheral vision or effective visual field (which is nearer to the gazing point than peripheral vision), and then answered questions regarding the positions and moving directions of the dots and the mental workload they experienced. The authors prepared two types of dotted patterns (fixed and moving) based on the perceptive characteristics of peripheral vision. The number of dots varied from one to six. The rate of misperception and participant mental workload were calculated. The results showed a tendency for the effect of the visual fields to depend on the type of dot pattern. It appears that the interface for peripheral vision may have resulted in a lower accuracy when fixed objects were presented, whereas fewer differences occurred when moving dots were shown. This implies that information with motion can be more suitable for interfaces utilizing peripheral vision. A larger amount of information and number of tasks resulted in lower accuracy and higher workload. Moreover, the relation between the number of dots and the rate of misperception (estimated based on percentage) suggests that the rate of misperception may increase significantly when either four or more fixed objects, or three or more moving objects, are presented.

著者

Yuan-Qing Fu Ju-Sheng Zheng Bo Yang Duo Li

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

pp.JE20140120, (Released:2015-03-14)

参考文献数

52

被引用文献数

15 33

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Epidemiological studies have suggested inconsistent associations between omega-3 polyunsaturated fatty acids (n-3 PUFAs) and prostate cancer (PCa) risk. We performed a dose-response meta-analysis of prospective observational studies investigating both dietary intake and circulating n-3 PUFAs and PCa risk. PubMed and EMBASE prior to February 2014 were searched, and 16 publications were eligible. Blood concentration of docosahexaenoic acid, but not alpha-linolenic acid or eicosapentaenoic acid, showed marginal positive association with PCa risk (relative risk for 1% increase in blood docosahexaenoic acid concentration: 1.02; 95% confidence interval, 1.00–1.05; I2 = 26%; P = 0.05 for linear trend), while dietary docosahexaenoic acid intake showed a non-linear positive association with PCa risk (P < 0.01). Dietary alpha-linolenic acid was inversely associated with PCa risk (relative risk for 0.5 g/day increase in alpha-linolenic acid intake: 0.99; 95% confidence interval, 0.98–1.00; I2 = 0%; P = 0.04 for linear trend), which was dominated by a single study. Subgroup analyses indicated that blood eicosapentaenoic acid concentration and blood docosahexaenoic acid concentration were positively associated with aggressive PCa risk and nonaggressive PCa risk, respectively. Among studies with nested case-control study designs, a 0.2% increase in blood docosapentaenoic acid concentration was associated with a 3% reduced risk of PCa (relative risk 0.97; 95% confidence interval, 0.94–1.00; I2 = 44%; P = 0.05 for linear trend). In conclusion, different individual n-3 PUFA exposures may exhibit different or even opposite associations with PCa risk, and more prospective studies, especially those examining dietary n-3 PUFAs and PCa risk stratified by severity of cancer, are needed to confirm the results.

著者

Haijun LIANG Hongyu YANG Bo YANG

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE TRANSACTIONS on Fundamentals of Electronics, Communications and Computer Sciences (ISSN:09168508)

巻号頁・発行日

vol.E96-A, no.1, pp.391-393, 2013-01-01

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A new paradigm for building Virtual Controller Model (VCM) for traffic flow simulator is developed. It is based on flight plan data and is applied to Traffic Flow Management System (TFMS) in China. The problem of interest is focused on the sectors of airspace and how restrictions to aircraft movement are applied by air traffic controllers and demand overages or capacity shortfalls in sectors of airspace. To estimate and assess the balance between the traffic flow and the capacity of sector in future, we apply Virtual Controller model, which models by the sectors airspace system and its capacity constraints. Numerical results are presented and illustrated by applying them to air traffic data for a typical day in the Traffic Flow Management System. The results show that the predictive capabilities of the model are successfully validated by showing a comparison between real flow data and simulated sector flow, making this method appropriate for traffic flow management system.