著者
Kenji Momo Takeo Yasu Seiichiro Kuroda Sonoe Higashino Eiko Mitsugi Hiromasa Ishimaru Kazumi Goto Atsuko Eguchi Kuniyoshi Sato Masahiro Matsumoto Takashi Shiga Hideki Kobayashi Reisuke Seki Mikako Nakano Yoshiki Yashiro Takuya Nagata Hiroshi Yamazaki Shou Ishida Naoki Watanabe Mihoko Tagomori Noboru Sotoishi Daisuke Sato Kengo Kuroda Dai Harada Hitoshi Nagasawa Takashi Kawakubo Yuta Miyazawa Kyoko Aoyagi Sachiko Kanauchi Kiyoshi Okuyama Satoshi Kohsaka Kohtaro Ono Yoshiyasu Terayama Hiroshi Matsuzawa Mikio Shirota
出版者
The Pharmaceutical Society of Japan
雑誌
Biological and Pharmaceutical Bulletin (ISSN:09186158)
巻号頁・発行日
vol.45, no.10, pp.1489-1494, 2022-10-01 (Released:2022-10-01)
参考文献数
19
被引用文献数
1

The aim of this study was to determine the proportion of near-miss dispensing errors in hospital pharmacies in Japan. A prospective multi-center observational study was conducted between December 2018 and March 2019. The primary objective was to determine the proportion of near-miss dispensing errors in hospital pharmacy departments. The secondary objective was to determine the predictive factors for near-miss dispensing errors using multiple logistic regression analysis. The study was approved by the ethical committee at The Institute of Medical Sciences, University of Tokyo, Japan. A multi-center prospective observational study was conducted in 20 hospitals comprising 8862 beds. Across the 20 hospitals, we assessed data from 553 pharmacists and 53039 prescriptions. A near-miss dispensing error proportion of 0.87% (n = 461) was observed in the study. We found predictive factors for dispensing errors in day-time shifts: a higher number of drugs in a prescription, higher number of quantified drugs, such as liquid or powder formula, in a prescription, and higher number of topical agents in a prescription; but we did not observe for career experience level for clinical pharmacists. For night-time and weekend shifts, we observed a negative correlation of near-miss dispensing errors with clinical pharmacist experience level. We found an overall incidence of near-miss dispensing errors of 0.87%. Predictive factors for errors in night-time and weekend shifts was inexperienced pharmacists. We recommended that pharmacy managers should consider education or improved work flow to avoid near-miss dispensing errors by younger pharmacists, especially those working night or weekend shifts.
著者
Yoshihiro Yabe Hiroshi Fujiki Hideki Kobayashi
出版者
West-Japanese Society of Orthopedics & Traumatology
雑誌
Orthopedics & Traumatology (ISSN:00371033)
巻号頁・発行日
vol.38, no.2, pp.435-438, 1989-10-25 (Released:2010-02-25)
参考文献数
6

Spontaneous rupture of the tendon during long-term systemic administration of steroids is rare and it is found only sporadically at the Achilles tendon.We report two cases of spontaneous rupture of the tendon during long-term systemic steroid therapy.One of the patients who was administered steroids for systemic lupus erythematosus developed rupture of the Achilles tendon, and the other treated for polyneuritis showed rupture of the tendon of the long head of the biceps brachii muscle.These two cases are considered to show that rupture of the tendon occurred due to degeneration and weakness of tendon tissue during long-term systemic steroid therapy.