- 著者
- Takuya Sakamoto Ryohei Imasaka Hirofumi Taki Toru Sato Mototaka Yoshioka Kenichi Inoue Takeshi Fukuda Hiroyuki Sakai
- 出版者
- The Institute of Electronics, Information and Communication Engineers
- 雑誌
- IEICE Electronics Express (ISSN:13492543)
- 巻号頁・発行日
- pp.12.20141197, (Released:2015-01-28)
- 参考文献数
- 23
- 被引用文献数
- 10 29
We demonstrate an accurate remote measurement of heartbeats using an ultra-wideband radar system. Although most conventional systems use either continuous waves or impulse-radio systems for remote vital monitoring, continuous waves suffer from non-stationary clutters, while impulse-radio systems cannot detect heartbeats. Our ultra-wideband radar system has a moderate fractional bandwidth intermediate of these systems, resulting in both the suppression of clutters and high sensitivity in measuring accurate heart rates even in a dynamic environment. A simultaneous measurement of the vital signal of a participant employing the ultra-wideband radar and electrocardiography reveals the high accuracy of the radar system in measuring the heart rate varying over time.
- 著者
- Hideto Kameda Hitoshi Tokuda Fumikazu Sakai Takeshi Johkoh Shunsuke Mori Yuji Yoshida Noboru Takayanagi Hirofumi Taki Yoshinori Hasegawa Kazuhiro Hatta Hisashi Yamanaka Makoto Dohi Shu Hashimoto Hidehiro Yamada Shinichi Kawai Tsutomu Takeuchi Kazuhiro Tateda Hajime Goto
- 出版者
- The Japanese Society of Internal Medicine
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- vol.50, no.4, pp.305-313, 2011 (Released:2011-02-15)
- 参考文献数
- 25
- 被引用文献数
- 27 60
Objective Acute-onset diffuse interstitial lung disease (AoDILD) in patients with rheumatoid arthritis (RA) has been a serious concern, especially for those under treatment with biological agents which may affect the presentation and outcome of AoDILD, including Pneumocystis pneumonia (PCP). Therefore, we conducted a retrospective, multi-center study of AoDILD in RA patients receiving biological agents. Methods Patients who developed AoDILD while receiving biological agents (infliximab, etanercept, adalimumab and tocilizumab) were enrolled in the study. Definite PCP was defined as patients who showed either P. jirovecii organisms in their respiratory samples by microscopic examination, or positive tests for both P. jirovicii DNA-PCR with respiratory samples and an elevated serum 1,3-β-D-glucan level above the cut-off value. Probable PCP was defined as either a positive test for P. jirovicii PCR or an elevated serum β-D-glucan level. Chest HRCT findings were evaluated and scored by two board-certified radiologists. Results The final diagnoses for 26 patients examined were definite PCP for 13 patients, probable PCP for 11, and methotrexate-associated pneumonitis in 2 patients. Definite and probable PCP cases were clinically indistinguishable. Generalized, diffuse ground-glass opacity (GGO) is the characteristic HRCT finding in patients with definite or probable PCP, which was different from our previous findings in RA patients, mostly without biologics, showing GGO distributed in a panlobular or multilobular manner. The clinical outcome was favorable by treatment with trimethoprim-sulfamethoxazole and glucocorticoids. Conclusion The possibility of PCP should be intensively investigated in RA patients developing AoDILD while receiving biological agents.