著者
下羅 弘樹 横田 裕思 松井 宏樹 野田 五十樹 柴山 明寛 羽田 靖史 目黒 淳一 Hiroki Shimora Hiroshi Yokota Hiroki Matsui Itsuki Noda Akihiro Shibayama Yashusi Hada Jun-ichi Meguro
雑誌
SIG-SAI = SIG-SAI
巻号頁・発行日
vol.3, no.2, pp.1-7, 2007-11-26

災害時情報共有のためのプロトコル、およびそのプロトコルを扱うサーバシステムを提案する。災害時において情報共有をいかに行うかは迅速な災害対応を行う上で重要であるが、実際の災害現場では紙ベースあるいは閉鎖的なシステムによる情報管理が行われており、十分な情報共有が行なわれていない。提案するシステムは、プロトコルとしてオープンな標準規格を用い、既存システムを柔軟に接続する事ができる。
著者
Kozo NAKAMURA Taku MIYASHO Sachiko NOMURA Hiroshi YOKOTA Tetsuya NAKADE
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.74, no.6, pp.751-756, 2012 (Released:2012-07-04)
参考文献数
19
被引用文献数
10 21

We performed proteomics analysis of the cerebrospinal fluid (CSF) of healthy dogs and dogs with meningoencephalitis of unknown etiology (MUE). By comparing two-dimensional electrophoreses (2DE), an upregulated spot was found in MUE dogs. This protein was identified as a neuron-specific enolase (NSE) by analysis with MALDI-TOF mass spectrometry. In comparing dot blots using an antibody against NSE, the NSE levels in the CSF of MUE dogs was significantly higher than that of the controls. NSE is a diagnostic marker of neuroendocrine tumors, brain injury and spinal cord trauma in humans. It seems that the NSE concentration in the CSF is increased by cellular destruction in canine encephalitis. Though elevation of NSE may not be specific in canine encephalitis because the NSE level was increased in other CNS diseases, further study including measurement with serum is necessary.
著者
Kozo NAKAMURA Taku MIYASHO Sachiko NOMURA Hiroshi YOKOTA Tetsuya NAKADE
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.1201110757, (Released:2012-01-18)
被引用文献数
12 21

We performed proteomics analysis of the cerebrospinal fluid (CSF) of healthy dogs and dogs with meningoencephalitis of unknown etiology (MUE). By comparing two-dimensional electrophoreses (2DE), an upregulated spot was found in MUE dogs. This protein was identified as a neuron-specific enolase (NSE) by analysis with MALDI-TOF mass spectrometry. In comparing dot blots using an antibody against NSE, the NSE levels in the CSF of MUE dogs was significantly higher than that of the controls. NSE is a diagnostic marker of neuroendocrine tumors, brain injury, spinal cord trauma in humans. It seems that the NSE concentration in the CSF is increased by cellular destruction in canine encephalitis. Though elevation of NSE may not be specific in canine encephalitis because NSE level was increased in other CNS disease, further study including the measurement with the serum is necessary.