著者

Kenji Sekiguchi Naoko Yasui Hisatomo Kowa Fumio Kanda Tatsushi Toda

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.55, no.21, pp.3181-3184, 2016-11-01 (Released:2016-11-01)

参考文献数

20

被引用文献数

9 11

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We herein present two cases of acute disseminated encephalomyelitis (ADEM) following vaccination against human papilloma virus (HPV). Case 1 experienced diplopia and developed an unstable gait 14 days after a second vaccination of Cervarix. Brain magnetic resonance imaging (MRI) showed an isolated small, demyelinating lesion in the pontine tegmentum. Case 2 experienced a fever and limb dysesthesia 16 days after a second vaccination of Gardasil. Brain MRI revealed hyperintense lesion in the pons with slight edema on a T2-weighted image. Both cases resolved completely. It is important to accumulate further data on confirmed cases of ADEM temporally associated with HPV vaccination.

著者

Takemasa ISHIKAWA Fumiya SANO Yugo NARITA Seiichi NAGANO Hideki MOCHIZUKI Hisatomo KOWA Kaoru KONISHI

出版者

Japan Society of Kansei Engineering

雑誌

International Symposium on Affective Science and Engineering (ISSN:24335428)

巻号頁・発行日

pp.1-4, 2023 (Released:2023-05-31)

参考文献数

11

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The transparent communication board (TCB) is a communication tool that is commonly employed by individuals with amyotrophic lateral sclerosis (ALS). Both the 50-letters and flick type TCB are prevalent in Japan. The purpose of this case study was to compare and investigate the speed of letter transmission and the subjective user impression associated with the use of the 50-letters and flick type TCB in ALS patients. The study included four ALS patients and four caregivers, who acted as communication partners. Participants used the 50-letters and flick type TCB at intervals ranging from one week to 90 days. They received video instructions on how to use each type of TCB and tried to transmit a total of 18 Japanese letters. We measured the time taken to transmit each word and the number of errors. Additionally, the participants were asked to complete a questionnaire assessing their subjective impressions of the TCB. Compared with the 50-letters type, the ALS patients and their partners tended to make fewer errors and preferred the flick type of TCB. However, the 50-letters type was easier to use to communicate if the patient and partner were not familiar with the flick type sequence. Our data suggest that the age of the patient and their partner, as well as the amount of experience using a smartphone, should be considered when choosing a TCB.

著者

Shunsuke MURATA Rei ONO Hisafumi YASUDA Rumi TANEMURA Yoshiaki KIDO Hisatomo KOWA

出版者

Japanese Society of Physical Therapy

雑誌

Physical Therapy Research (ISSN:21898448)

巻号頁・発行日

vol.24, no.2, pp.112-119, 2021-08-20 (Released:2021-08-20)

参考文献数

21

被引用文献数

3

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Objective: The purpose of this study is to investigate the effect of an intervention combining exercise and cognitive activity on cognitive function in healthy older adults. Methods: This pilot randomized controlled trial recruited 33 eligible, healthy communitydwelling older adults (mean age, 77.1 years old; women, 51.5%), who were divided into intervention and waitlist control groups. The intervention group was engaged weekly in a group activity comprising exercise and discussions of homework, which included reading aloud, simple arithmetic, and simple activities, like spotting differences, for cognitive stimulation. They were also required to complete cognitive activity homework twice a week. The waitlist control group received no intervention. The main outcomes were cognitive function assessed using the Mini-Mental State Examination, delayed recall score on the Logical Memory IIA of the Wechsler Memory Scale Revised, Trail Making Test, and digit symbol substitution test. Results: According to the results, Mini-Mental State Examination scores were maintained in the intervention group but declined in the control group [Mean change in outcomes in control group (95% confidence interval): -1.68 (-2.89 to -0.48) ]. Additional mean change in outcomes in intervention group were found [1.68 (0.02 to 3.35) ]. Conclusions: Interventions combining exercise and cognitive activity can be helpful for preserving cognitive function in healthy older adults.