著者

Dong-In KIM Hakhyun KIM Purum SON Ji-Houn KANG Byeong-Teck KANG Mhan-Pyo YANG

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.16-0647, (Released:2017-06-29)

被引用文献数

17

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The present study aimed to determine whether circulating serum concentrations of 25-hydroxyvitamin D [25-(OH)D] differed between healthy dogs and dogs with acute pancreatitis (AP). Twenty-two healthy dogs and twenty client-owned dogs with AP were enrolled in the study. Serum concentrations of 25-(OH)D, blood ionized calcium (iCa), and serum C-reactive protein (CRP) were measured. Concentrations of serum 25-(OH)D and blood iCa in dogs with AP were significantly lower than those of healthy dogs, and serum concentrations of CRP in dogs with AP were significantly higher than those of healthy dogs. A significant difference in 25-(OH)D serum concentrations was observed between survivor and non-survivor dogs with AP. After resolution of clinical signs, concentrations of serum 25-(OH)D, blood iCa, and serum CRP did not differ compared to those before treatment. This study shows that dogs with AP exhibit decreased 25-(OH)D levels, which might be associated with calcium imbalances and mortality rate in canine AP.

著者

Haengbok CHEON Wooshin CHOI Youngjae LEE Donghoon LEE Juhyung KIM Ji-Houn KANG Kijeong NA Jinhwa CHANG Dongwoo CHANG

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.74, no.11, pp.1461-1467, 2012 (Released:2012-12-01)

参考文献数

30

被引用文献数

5 18 1

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The aim of this study was to assess age-related changes and anatomic variation in trabecular bone mineral density (tBMD) using quantitative computed tomography (QCT) in normal cats. Seventeen normal cats were included in this study and divided into the following 3 age groups:6 years (n=3). A computed tomographic scan of each vertebra from the 12th thoracic to the 7th lumbar spine and the pelvis was performed with a bone-density phantom (50, 100 and 150 mg/cm3, calcium hydroxyapatite, CIRS phantom®). On the central transverse section, the elliptical region of interest (ROI) was drawn to measure the mean Hounsfield unit (HU) value. Those values were converted to equivalent tBMD (mg/cm3) by use of the bone-density phantom and linear regression analysis (r2 >0.95). The mean tBMD value of the thoracic vertebrae (369.4 ± 31.8 mg/cm3) was significantly higher than that of the lumbar vertebrae (285 ± 58.1 mg/cm3). The maximum tBMD occurred at the T12, T13 and L1 levels in all age groups. There was a statistically significant difference in the mean tBMD value among the 3 age groups at the T12 (PPP=0.013), respectively. The present study suggests that age-related changes and anatomic variation in tBMD values should be considered when assessing tBMD using QCT in cats with bone disorders.

著者

Haengbok CHEON Wooshin CHOI Youngjae LEE Donghoon LEE Juhyung KIM Ji-Houn KANG Kijeong NA Jinhwa CHANG Dongwoo CHANG

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.11-0579, (Released:2012-07-06)

被引用文献数

5 18

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The aim of this study was to assess age-related changes and anatomic variation in trabecular bone mineral density (tBMD) using quantitative computed tomography (QCT) in normal cats. Seventeen normal cats were included in this study and divided into the following 3 age groups: <6 months (n=4); 2–5 years (n=10); and >6 years (n=3). A computed tomographic scan of each vertebra from the 12th thoracic to the 7th lumbar spine, and the pelvis was performed with a bone-density phantom (50, 100, and 150 mg/cm3, calcium hydroxyapatite, CIRS phantom®). On the central transverse section, the elliptical region of interest (ROI) was drawn to measure the mean Hounsfield unit (HU) value. Those values were converted to equivalent tBMD (mg/cm3) by use of the bone-density phantom and linear regression analysis (r2>0.95). The mean tBMD value of the thoracic vertebrae (369.4 ± 31.8 mg/cm3) was significantly higher than that of the lumbar vertebrae (285 ± 58.1 mg/cm3). The maximum tBMD occurred at the T12, T13, and L1 levels in all age groups. There was a statistically significant difference in the mean tBMD value among the 3 age groups at the T12 (P<0.001), T13 (P<0.001), and L4 levels (P=0.013), respectively. The present study suggests that age-related changes and anatomic variation in tBMD values should be considered when assessing tBMD using QCT in cats with bone disorders.