著者

Hae-Won JUNG Hee-Chun LEE Ji-Hyun KIM Hyo-Mi JANG Jong-Hyun MOON Jung-Hyang SUR Jeongim HA Dong-In JUNG

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.14-0001, (Released:2014-08-13)

被引用文献数

3 12

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An 8-year-old intact male Belgian Malinois, weighing 37.2 kg, was referred for evaluation due to right side facial paresis, ataxia and a two-month history of decreased cognitive ability. Physical and neurological examinations revealed mild depression, left-sided head tilt, right-sided facial paresis and ataxia. A well-demarcated, broad-based cerebellar mass and hyperostosis were found on CT imaging of the brain. Based on these CT findings, a cerebellar meningioma was strongly suspected. Hydroxyurea and prednisolone were administered; after 4 weeks, there was reduction in mass size as compared to initial CT results. However, the mass size was found to have grown 6 weeks after hydroxyurea treatment. We then prescribed a combination of imatinib mesylate and hydroxyurea. Two weeks following combination treatment, the mass size had reduced significantly. The mass continuously decreased in size until the patient died during anesthesia. Cerebellar transitional meningioma was confirmed by histopathologic examination. To the author’s knowledge, this is the first reported case of imatinib mesylate plus hydroxyurea therapy for the treatment of meningioma in veterinary medicine.

著者

Hee-Chun LEE Ji-Hyun KIM Cho-Hee JEE Jae-Hoon LEE Jong-Hyun MOON Na-Hyun KIM Jung-Hyang SUR Kyu-Woan CHO Byeong-Teck KANG Jeongim HA Dong-In JUNG

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.13-0315, (Released:2014-03-20)

被引用文献数

1 8

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A 9-year-old castrated male Shih-tzu dog was referred to us because of chronic vomiting. The patient’s hematological, radiographic, ultrasonographic, endoscopic, and histological examinations were evaluated for diagnosis. Hematologic analysis indicated moderate anemia and azotemia. Based on imaging study, oval-shape mass was identified in gastric pylorus area. A proliferative mass was found on endoscopic examination and we performed biopsy using grasping forceps. The histopathological findings of the biopsy specimens indicated hypertrophic gastritis and Y-U pyloroplasty was performed. However, the histopathological examination of surgically resected mass was identified as tubular adenocarcinoma of stomach. Then carboplatin chemotherapy was performed 4 times for 13 weeks. The clinical sign such as vomiting were resolved gradually after surgery and chemotherapy, and the patient’s condition was managed favorably until recently (30 months after surgery). This case report demonstrated clinical features, imaging studies, endoscopic characteristics, histopathological and immunohistochemical features of gastric tubular adenocarcinoma as early gastric cancer in a dog.

著者

Dong-In JUNG Hee-Chun LEE Jeongim HA Hae-Won JUNG Joon-Hyeonk JEON Jong-Hyun MOON Jae-Hoon LEE Na-Hyun KIM Jung-Hyang SUR Byeong-Teck KANG Kyu-Woan CHO

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.12-0503, (Released:2013-08-13)

被引用文献数

1 4

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A 4-year-old female Maltese (case 1), a 9-year-old castrated male Shih-Tzu (case 2) and 2-year-old female Pomeranian (case 3) were presented because of neurological signs such as head tilt, ataxia, circling and paresis. Three cases were tentatively diagnosed to meningoencephalitis of unknown etiology based on computed tomography scan and cerebrospinal fluid analysis. All patients were managed with cyclosporine plus prednisolone therapy. The survival times of three patients were 170, 70 and 21 days, respectively. After cases expired, we performed necropsy and histopathological examination for definitive diagnosis. Based on the necropsy, histopathological and immunohistochemical examinations, case 1, 2 and 3 were definitely diagnosed to necrotizing meningoencephalitis, necrotizing leukoencephlaitis and granulomatous meningoencephalitis, respectively. This case report demonstrated that the clinical findings, brain CT characteristics, histopathological and immunohistochemical features of NME, NLE and GME in dogs and discussed about the reason of relatively short survival times under cyclosporine plus prednisolone therapy.

著者

So-Jeung MOON Ju-Won KIM Jung-Hyang SUR Soon-Wuk JEONG Hee-Myung PARK

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.73, no.12, pp.1677-1679, 2011 (Released:2012-01-06)

参考文献数

10

被引用文献数

1 4

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A 14-year-old Maltese dog presented for complete medical examination due to intermittent vomiting and diarrhea observed during the previous two days. A single, solitary, lobulated cystic mass was observed in the liver upon ultrasonographic and computed tomographic examination. After surgical hepatic resection to remove the mass, histological examination revealed a multilocular cyst lined by cuboidal to columnar epithelial cells, which is consistent with biliary cystadenoma. Here, we report the clinical, clinicopathological, histopathological, and diagnostic imaging findings of biliary cystadenoma in a dog.

著者

Jung-ha LEE Jong-hoon LEE Hun-young YOON Na-hyun KIM Jung-hyang SUR Soon-wuk JEONG

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.1112200732, (Released:2011-12-26)

被引用文献数

5 10

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A six-year-old intact female Maltese dog weighing 3.8 kg presented with a history of mild lameness and swelling on both forelimbs. Radiographic and computed tomographic views revealed an extensive periosteal reaction in all four limbs and a large round mass on the right middle lung lobe. A total lobectomy was performed and pulmonary adenosquamous carcinoma was histologically confirmed. A diagnosis of hypertrophic osteopathy (HO) secondary to a lung tumor was made. Periosteal proliferation decreased significantly after surgery; however, there was evidence of dyspnea, mass recurrence, and periosteal reaction three months post-operatively. This is the first case report of pulmonary adenosquamous carcinoma with HO in a dog in which we describe clinical, imaging, surgical, and histological findings.