著者

Mari Ogura Yuji Morita Wakako Takabe Masayuki Yagi Fuka Okuda Misato Kon Kenichi Asada Tetsuro Urata Hiroshi Yatou Hiroomi Maeda Yoshikazu Yonei

出版者

Society for Glycative Stress Research

雑誌

Glycative Stress Research (ISSN:21883602)

巻号頁・発行日

vol.7, no.1, pp.29-41, 2020 (Released:2020-05-08)

参考文献数

31

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Objective: We investigated the effects of the intake of ostrich meat (OM), which is characterized by high protein and low fat, on the body, focusing on protein and amino acid metabolism and growth hormone (GH) secretion. Methods: Plasma amino acid levels, growth hormone (GH) secretion after exercise and autonomic nervous function (device used: VM500 [Fatigue Science Laboratory Inc.]) were measured in 12 healthy subjects (33.3 ± 6.9 years old, BMI 21.6 ± 1.6) after ingestion of the test food (OM) or control food for one week each. Results: A significant increase in the blood levels of branched-chain amino acids (BCAAs), lysine and histidine, and an increase in those for 1-methylhistidine and 3-methylhistidine, which are the indicators of muscle protein breakdown, were observed after the intake of OM, suggesting that protein metabolism in the muscles was activated. Subclass analysis excluding cases with high GH before exercise load showed a significant increase in GH secretion after a walking exercise (30 min) only after the intake of OM. The autonomic nervous function test did not reveal any significant findings. There were no OM-related adverse events during the study. Conclusion: OM is a low-fat meat containing physiologically significant amino acids in large quantities, and it was suggested that OM could be safe and suitable for a protein and amino acid supplement.

著者

Motoki ENDO Yasuo HARUYAMA Takashi MUTO Mikio YUHARA Kenichi ASADA Rika KATO

出版者

National Institute of Occupational Safety and Health

雑誌

Industrial Health (ISSN:00198366)

巻号頁・発行日

vol.51, no.2, pp.165-171, 2013 (Released:2013-08-31)

参考文献数

33

被引用文献数

14 19

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There have been few epidemiological studies on recurrent sickness absence due to depression after returning to work (RTW). The objective of this study was to investigate the prognosis of workers who are RTW with depression in a Japanese company. This study employed a descriptive epidemiology study design. Subjects of this study were 540 employees who worked full-time and were registered in the Health Data System and returned to work from April 2002 to March 2008 after their first leave of absence due to depression. We investigated the recurrence of sickness absence due to depression after returning to work using the Kaplan-Meier survival curve method. During the 8.5 yr follow-up period, almost half of the RTW employees experienced recurrent sickness absence. There was a steep increase in recurrent rates the first two years after RTW, and 85.2% of total recurrence of sickness absence had occurred within three years after the index episode.