- 著者
- Minoru Kurisu Masayuki Imai
- 出版者
- The Biophysical Society of Japan
- 雑誌
- Biophysics and Physicobiology (ISSN:21894779)
- 巻号頁・発行日
- pp.e210002, (Released:2023-12-19)
How do the living systems emerge from non-living molecular assemblies? What physical and chemical principles supported the process? To address these questions, a promising strategy is to artificially reconstruct living cells in a bottom-up way. Recently, the authors developed the “synthetic minimal cell” system showing recursive growth and division cycles, where the concepts of information molecules, metabolic pathways, and cell reproduction were artificially and concisely redesigned with the vesicle-based system. We intentionally avoided using the sophisticated molecular machinery of the biological cells and tried to redesign the cells in the simplest forms. This review focuses on the similarities and differences between the biological cells and our synthetic minimal cell concerning each concept of cells. Such comparisons between natural and artificial cells will provide insights on how the molecules should be assembled to create living systems to the wide readers in the field of synthetic biology, artificial cells, and protocells research. This review article is an extended version of the Japanese article “Growth and division of vesicles coupled with information molecules,” published in SEIBUTSU-BUTSURI vol. 61, p. 378-381 (2021).
- 著者
- Masayuki IMAI
- 出版者
- The Crystallographic Society of Japan
- 雑誌
- Nihon Kessho Gakkaishi (ISSN:03694585)
- 巻号頁・発行日
- vol.42, no.2, pp.129-138, 2000-04-30 (Released:2010-09-30)
- 参考文献数
- 22
In this lecture I explain basic concepts of small angle scattering and their application to structural analysis of polymer materials. The small angle scattering plays an important role to elucidate fundamental problems in polymer physics.