- 著者
- 
             
             Keiko Yamasaki
             
             Hiroyuki Sawatari
             
             Nao Konagai
             
             Chizuko A. Kamiya
             
             Jun Yoshimatsu
             
             Jun Muneuchi
             
             Mamie Watanabe
             
             Terunobu Fukuda
             
             Atsushi Mizuno
             
             Ichiro Sakamoto
             
             Kenichiro Yamamura
             
             Tomoko Ohkusa
             
             Hiroyuki Tsutsui
             
             Koichiro Niwa
             
             Akiko Chishaki
             
          
- 出版者
- The Japanese Circulation Society
- 雑誌
- Circulation Journal (ISSN:13469843)
- 巻号頁・発行日
- vol.83, no.11, pp.2257-2264, 2019-10-25 (Released:2019-10-25)
- 参考文献数
- 38
- 被引用文献数
- 
             
             
             5
             
             
          
        
        Background:The average maternal age at delivery, and thus the associated maternal risk are increasing including in women with congenital heart disease (CHD). A comprehensive management approach is therefore required for pregnant women with CHD. The present study aimed to investigate the factors determining peripartum safety in women with CHD.Methods and Results:We retrospectively collected multicenter data for 217 pregnant women with CHD (age at delivery: 31.4±5.6 years; NYHA classifications I and II: 88.9% and 7.4%, respectively). CHD severity was classified according to the American College of Cardiology/American Heart Association guidelines as simple (n=116), moderate complexity (n=69), or great complexity (n=32). Cardiovascular (CV) events (heart failure: n=24, arrhythmia: n=9) occurred in 30 women during the peripartum period. Moderate or great complexity CHD was associated with more CV events during gestation than simple CHD. CV events occurred earlier in women with moderate or great complexity compared with simple CHD. Number of deliveries (multiparity), NYHA functional class, and severity of CHD were predictors of CV events.Conclusions:This study identified not only the severity of CHD according to the ACC/AHA and NYHA classifications, but also the number of deliveries, as important predictive factors of CV events in women with CHD. This information should be made available to women with CHD and medical personnel to promote safe deliveries.