著者

Tatsuo Tokeshi Ayumi Date Hiroyuki Miura Leon Kumasaka Tetsuo Arakawa Kazuhiro Nakao Shigefumi Fukui Takuya Hasegawa Masanobu Yanase Michio Nakanishi Teruo Noguchi Satoshi Yasuda Yoichi Goto

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-22-0606, (Released:2023-02-17)

参考文献数

37

被引用文献数

3

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Background: Whether the magnitude and predictors of improvement in exercise capacity after cardiac rehabilitation (CR) are the same between young-old (YO) and octogenarian (OCT) patients with acute myocardial infarction (AMI) is unknown.Methods and Results: We studied 284 YO (age range 65–69 years; mean [±SD] 67±1 years) and 65 OCT (age range ≥80 years; mean [±SD] 83±2 years) patients who participated in a post-AMI CR program. After 3 months of CR, peak oxygen uptake (PV̇O2) measured during cardiopulmonary exercise testing improved significantly in both age groups (P<0.01), although the percentage increase in PV̇O2(%∆PV̇O2) was significantly smaller in the OCT than YO group (5.4±13.7% vs. 10.0±12.8%; P<0.01). Multiple regression analysis demonstrated that independent predictors of %∆PV̇O2were the number of outpatient CR (OPCR) sessions attended (P=0.015), left ventricular ejection fraction (P=0.028), and baseline PV̇O2(P=0.0007) in the YO group; and the number of sessions attended (P=0.018), atrial fibrillation (P=0.042), and the presence of nutritional risk (Geriatric Nutritional Risk Index ≤98; P=0.036) in the OCT group.Conclusions: The predictors of improvement in exercise capacity after CR differed between the YO and OCT patients with AMI. To obtain a greater improvement in PV̇O2in CR, frequent OPCR session attendance may be necessary in both groups; in addition, particularly in OCT patients, better nutritional status may be important.

著者

Kayo Misumi Michio Nakanishi Hiroyuki Miura Ayumi Date Tatsuo Tokeshi Leon Kumasaka Tetsuo Arakawa Kazuhiro Nakao Takuya Hasegawa Shigefumi Fukui Masanobu Yanase Teruo Noguchi Kengo Kusano Satoshi Yasuda Yoichi Goto

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-20-1300, (Released:2021-06-30)

参考文献数

33

被引用文献数

5

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Background:In patients with chronic heart failure with reduced ejection fraction (HFrEF), cardiac resynchronization therapy (CRT) improves left ventricular ejection fraction (LVEF) and exercise-based cardiac rehabilitation (ECR) enhances exercise capacity. This study examined the relationship between the 2 responses.Methods and Results:Sixty-four consecutive HFrEF patients who participated in a 3-month ECR program after CRT were investigated. Patients were categorized according to a median improvement in peak oxygen uptake (PV̇O2) after ECR of 7% as either good (n=32; mean percentage change in PV̇O2[%∆PV̇O2]=23.2%) or poor (n=32; mean %∆PV̇O2=2.5%) responders. There was no significant difference in baseline characteristics between the good and poor responders, except for PV̇O2(51% vs. 59%, respectively; P=0.01). The proportion of good CRT responders was similar between the good and poor responders (%∆LVEF ≥10%; 53% vs. 47%, respectively; P=NS). Overall, there was no significant correlation between %∆LVEF after CRT and %∆PV̇O2after ECR. Notably, among poor CRT responders (n=32), the prevalence of atrial fibrillation (0% vs. 29%; P<0.03) and baseline PV̇O2(48% vs. 57%; P<0.05) were significantly lower among those with a good (n=15) than poor (n=17) response to ECR.Conclusions:In patients with HFrEF, good ECR and CRT responses are unrelated. A good PV̇O2response to ECR can be achieved even in poor CRT responders, particularly in those with a sinus rhythm or low baseline PV̇O2.

著者

Fumio Terasaki Arata Azuma Toshihisa Anzai Nobukazu Ishizaka Yoshio Ishida Mitsuaki Isobe Takayuki Inomata Hatsue Ishibashi-Ueda Yoshinobu Eishi Masafumi Kitakaze Kengo Kusano Yasushi Sakata Noriharu Shijubo Akihito Tsuchida Hiroyuki Tsutsui Takatomo Nakajima Satoshi Nakatani Taiko Horii Yoshikazu Yazaki Etsuro Yamaguchi Tetsuo Yamaguchi Tomomi Ide Hideo Okamura Yasuchika Kato Masahiko Goya Mamoru Sakakibara Kyoko Soejima Toshiyuki Nagai Hiroshi Nakamura Takashi Noda Takuya Hasegawa Hideaki Morita Tohru Ohe Yasuki Kihara Yoshihiko Saito Yukihiko Sugiyama Shin-ichiro Morimoto Akira Yamashina on behalf of the Japanese Circulation Society Joint Working Group

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.83, no.11, pp.2329-2388, 2019-10-25 (Released:2019-10-25)

参考文献数

355

被引用文献数

95 237

著者

Makoto Amaki Nao Konagai Masashi Fujino Shouji Kawakami Kazuhiro Nakao Takuya Hasegawa Yasuo Sugano Yoshio Tahara Satoshi Yasuda

出版者

日本循環器学会

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-16-1222, (Released:2016-12-10)

参考文献数

10

被引用文献数

2

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The American Heart Association (AHA) Scientific Sessions 2016 were held on November 12–16 at the Ernest N. Morial Convention Center, New Orleans, LA. This 5-day event featured cardiovascular clinical practice covering all aspects of basic, clinical, population, and translational content. One of the hot topics at AHA 2016 was precision medicine. The key presentations and highlights from the AHA Scientific Sessions 2016, including “precision medicine” as one of the hot topics, are herein reported.

著者

Toru Miyama Takuya Hasegawa

出版者

(公社)日本気象学会

雑誌

SOLA (ISSN:13496476)

巻号頁・発行日

vol.10, pp.5-9, 2014 (Released:2014-02-06)

参考文献数

24

被引用文献数

3 9

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A regional atmospheric model was employed to demonstrate that a strong westerly wind, which occurred around December 2001 prior to the 2002/03 El Niño event, was enhanced by sea surface temperature gradient along the equator in the western Pacific warm pool region. Furthermore, a regional oceanic model was employed to demonstrate that the enhanced westerly wind event substantially increased oceanic Kelvin wave response along the equatorial Pacific Ocean.

著者

Yusuke ASAKURA Takuya HASEGAWA Shu YIN

出版者

The Ceramic Society of Japan

雑誌

Journal of the Ceramic Society of Japan (ISSN:18820743)

巻号頁・発行日

vol.128, no.12, pp.1061-1065, 2020-12-01 (Released:2020-12-01)

参考文献数

29

被引用文献数

5

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Attention has recently been paid to oxyfluorides, one of the mixed anion materials, because they possess unique properties for many kinds of application fields. Because the general synthesis processes for oxyfluorides are based on troublesome methods, novel safe and facile processes are required. In this study, MoO3 was solvothermally reacted with KF, RbF, and CsF at 200 °C to form potassium, rubidium, and cesium molybdenum oxyfluorides. The reaction of MoO3 with KF and RbF led to the formation of K3MoO3F3 and Rb3MoO3F3 with a known structure, respectively, while the reaction of MoO3 with CsF induced an unknown phase which should be Cs3MoO3F3 with the similar structure to those of K3MoO3F3 and Rb3MoO3F3. A3MoO3F3 (A = K, Rb, and Cs) has not been synthesized under liquid phase until now, and this research clarified this kind of the solvothermal reaction can lead to the formation of unique oxyfluorides at low temperature. In addition, Cs3MoO3F3 was converted into Cs3Mo2O6F3 by treatment with methanol, suggesting the instability of Cs3MoO3F3. This kind of conversion reaction from one oxyfluoride to the other oxyfluoride has not been reported, and the development of such chemical conversion may lead to the formation of new oxyfluorides.

著者

Mikio Shiba Yasuo Sugano Yoshihiko Ikeda Hatsue Ishibashi-Ueda Takahiro Ohara Takuya Hasegawa Hideaki Kanzaki Toshihisa Anzai

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.55, no.7, pp.751-754, 2016 (Released:2016-04-01)

参考文献数

11

被引用文献数

2 5

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A 74-year-old man, who had a history of a mitral valve replacement for rheumatic heart disease (RHD) 30 years previously, was admitted with progressive heart failure. Massive calcification was observed around the left atrium on multidetector CT, in addition to a late gadolinium enhancement (LGE)-positive layer adjacently outside of the calcification on MRI. He underwent a second mitral valve replacement for the prosthetic valve failure. Pathohistological analyses of a tissue section of the left atrial wall from a surgical specimen revealed lymphocyte and macrophage infiltration that coincided with the LGE-positive layer on MRI, suggesting the existence of sustained active inflammation even after the long period of RHD.