著者

Akiko MIZOTE Mika YAMADA Chiyo YOSHIZANE Norie ARAI Kazuhiko MARUTA Shigeyuki ARAI Shin ENDO Rieko OGAWA Hitoshi MITSUZUMI Toshio ARIYASU Shigeharu FUKUDA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.62, no.6, pp.380-387, 2016 (Released:2017-02-16)

参考文献数

22

被引用文献数

13 33

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We previously performed animal studies that suggested that trehalose potentially prevents the development of metabolic syndrome in humans. To evaluate this possibility, we examined whether trehalose suppressed the progression of insulin resistance in a placebo-controlled, double-blind trial in 34 subjects with a body mass index (BMI) ≥23. The subjects were divided into two groups and were assigned to ingest either 10 g/d of trehalose or sucrose with meals for 12 wk. During the study, body composition and blood biochemical parameters were measured at week 0, 8, and 12. These parameters were also measured 4 wk after the end of intake to confirm the washout of test substances. In the trehalose group, blood glucose concentrations after a 2-h oral glucose tolerance test significantly decreased following 12 wk of intake in comparison with baseline values (0 wk). When a stratified analysis was performed in the subjects whose percentage of truncal fat approached the high end of the normal range, the change in body weight, waist circumference, and systolic blood pressure were significantly lower in the trehalose group than in the sucrose group. Our data indicated that a daily intake of 10 g of trehalose improved glucose tolerance and progress to insulin resistance. Furthermore, these results suggested that trehalose can potentially reduce the development of metabolic syndrome and associated lifestyle-related diseases, such as type 2 diabetes.

著者

中村 友香 藤澤 憲 中西 裕子 西林 佳人 守谷 安津蓉 小河 理恵子 髙橋 真一郎 亀井 有美 高橋 眞琴 Yuka NAKAMURA Ken FUJISAWA Yuko NAKANISHI Yoshito NISHIBAYASHI Atsuyo MORIYA Rieko OGAWA Shinichiro TAKAHASHI Yumi KAMEI Makoto TAKAHASHI

出版者

鳴門教育大学地域連携センター

雑誌

鳴門教育大学学校教育研究紀要 = Bulletin of Center for Collaboration in Community Naruto University of Education (ISSN:18806864)

巻号頁・発行日

no.35, pp.29-38, 2021-02

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新型コロナウイルス感染症(以下,COVID-19)の対応に際して,緊急事態宣言発出後,筆者らが関与する教育関係,福祉関係,医療関係の最前線での実践現場においては,これまでの実践内容にない対応を求められた。本論文では,筆者らが関与している教育関係,福祉関係,医療関係の最前線での実践現場についての現状と課題を把握していくことを目的とした。現状として,実践現場での感染症予防対策以外にも教材作成や労務上の対応が求められており,課題として,児童・生徒,利用者の心のケアや実践者自身のバーンアウトへの対応必要性も示唆された。