著者
Chun-Ho PARK Sayaka KUBONIWA Ryo MURAKAMI Nozomi SHIWA Satoshi INOUE Kazunori KIMITSUKI Ma. Ricci R. GOMEZ Mark Joseph M. ESPINO Alpha Grace B. CABIC Sheila Marie C. ESPOSO Daria L. MANALO
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.83, no.10, pp.1563-1569, 2021 (Released:2021-10-05)
参考文献数
27
被引用文献数
2

The rabies virus is one of the most neurotropic of all viruses infecting mammals. During the terminal phases of infection, the virus spreads to peripheral tissues, including the skin. The external skin of the nose, called the nasal planum, is a sensory organ where numerous nerve bundles and terminal nerves are distributed. Therefore, the nasal planum is expected to serve as a postmortem diagnostic material. However, the distribution of rabies virus antigens in the nasal planum in rabid animals has not yet been studied. In this study, the nasal planum was obtained from 45 rabid dogs. In all rabid dogs, the viral antigen was detected in the peripheral nerve tissues, Merkel cells, and squamous cells. The viral antigen in the epidermis exhibited three patterns: first, a diffuse positive pattern from the basal layer to the squamous layer; second, a reticular positive pattern along the cell membrane in the squamous layer; and third, a basal layer pattern of the epidermis. In the dermis, viral antigens were detected more often in lamellated corpuscles just beneath the rete pegs. These results suggest that the nasal planum could serve as a useful alternative source for postmortem diagnosis in rabies endemic countries.
著者
Chun-Ho PARK Sayaka KUBONIWA Ryo MURAKAMI Nozomi SHIWA Satoshi INOUE Kazunori KIMITSUKI Ma. Ricci R. GOMEZ Mark Joseph M. ESPINO Alpha Grace B. CABIC Sheila Marie C. ESPOSO Daria L. MANALO
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.21-0438, (Released:2021-09-02)
被引用文献数
2

The rabies virus is one of the most neurotropic of all viruses infecting mammals. During the terminal phases of infection, the virus spreads to peripheral tissues, including the skin. The external skin of the nose, called the nasal planum, is a sensory organ where numerous nerve bundles and terminal nerves are distributed. Therefore, the nasal planum is expected to serve as a postmortem diagnostic material. However, the distribution of rabies virus antigens in the nasal planum in rabid animals has not yet been studied. In this study, the nasal planum was obtained from 45 rabid dogs. In all rabid dogs, the viral antigen was detected in the peripheral nerve tissues, Merkel cells, and squamous cells. The viral antigen in the epidermis exhibited three patterns: first, a diffuse positive pattern from the basal layer to the squamous layer; second, a reticular positive pattern along the cell membrane in the squamous layer; and third, a basal layer pattern of the epidermis. In the dermis, viral antigens were detected more often in lamellated corpuscles just beneath the rete pegs. These results suggest that the nasal planum could serve as a useful alternative source for postmortem diagnosis in rabies endemic countries.
著者
村上 亮 Ryo Murakami
出版者
同志社大学人文科学研究所
雑誌
社会科学 = The Social Science(The Social Sciences) (ISSN:04196759)
巻号頁・発行日
vol.49, no.4, pp.133-159, 2020-02-28

第一次世界大戦の直接的な契機となったサライェヴォ事件の犯人,セルビア人青年ガヴリロ・プリンツィプの評価については「英雄」と「テロリスト」のあいだで一致をみていない。これは、長年にわたり続いている第一次大戦の開戦責任問題に深く関わる問題といえる。本稿は,このようなプリンツィプの捉え方の変遷をたどるとともに,近年,開戦責任論争において批判的に論じられるセルビアの動きを分析するものである。