著者

James K. CHAMBERS Shinya IWASAKI Shigeki IMAMOTO Yuya NAKAMOTO Kazuyuki UCHIDA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.84, no.5, pp.634-637, 2022 (Released:2022-05-01)

参考文献数

16

被引用文献数

2

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A two-months-old, male, mixed breed cat presented with epileptic seizures. The cat was diagnosed with drug-resistant epilepsy, and died at 3-years of age. No gross lesion was found at necropsy. Histopathologically, the dentate gyrus granule cell layer of the hippocampus was irregularly arranged. Granule cells were dispersed and ectopic cells were sporadically observed in the molecular layer. The granule cells had an enlarged cytoplasm and swollen nucleus. Immunohistochemistry for NeuN and GFAP confirmed severe neuronal loss and mild gliosis in CA1. Binucleation and ischemic change were observed in the remaining pyramidal cells. This report describes a case of feline temporal lobe epilepsy and hippocampal sclerosis associated with dentate gyrus malformation.

著者

福原 宏幸 勝部 麗子 永岡 正己 岩崎 晋也 牧里 毎治 Hiroyuki Fukuhara Reiko Katsube Masami Nagaoka Shinya Iwasaki Tsuneji Makisato

雑誌

Human Welfare : HW (ISSN:18832733)

巻号頁・発行日

vol.5, no.1, pp.87-113, 2013-03-10

著者

福原 宏幸 勝部 麗子 永岡 正己 岩崎 晋也 牧里 毎治 Hiroyuki Fukuhara Reiko Katsube Masami Nagaoka Shinya Iwasaki Tsuneji Makisato

雑誌

Human Welfare : HW (ISSN:18832733)

巻号頁・発行日

vol.5, no.1, pp.87-113, 2013-03-10