著者

TAKAHASHI Kazuhiro KAWAGUCHI Satoru SATOH Kohki KAWAGUCHI Hideki TIMOSHKIN Igor GIVEN Martin MACGREGOR Scott

出版者

Japan Society of Applied Physics

雑誌

Japanese Journal of Applied Physics (ISSN:00214922)

巻号頁・発行日

vol.58, no.2, pp.026001, 2019-01-21

被引用文献数

1

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The concentration variations of reactive oxygen/nitrogen species in water, such as H2O2, NO2 −, and NO3 − generated by pulsed-discharge plasma exposure, are calculated using reaction rates of chemical reactions and acid-base equilibrium in water. The calculated concentrations and pH values are in good agreement with measured data within the range where the significant changes of the measured data are observed. The rate constant for ONOOH generation is estimated to be 7.8 × 103 M−2 s−1, and this value is in good agreement with previously reported values. The generation rates of H2O2, NO2 −, and NO3 − are estimated to be 7.70 × 10−7, 4.10 × 10−7, and 1.10 × 10−7 M s−1, respectively.

著者

Oshiro Yukio Takahashi Kazuhiro Sasaki Ryoko Kondo Tadashi Sakashita Shingo Ohkohchi Nobuhiro

出版者

Baishideng Publishing Group Inc.

雑誌

World journal of gastroenterology (ISSN:10079327)

巻号頁・発行日

vol.19, no.40, pp.6934-6938, 2013-10

被引用文献数

10

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Patients with Stage IV cholangiocarcinoma are currently not considered to be surgical candidates and are typically offered systemic chemotherapy. Recently, several novel systemic chemotherapy regimens have allowed an initially unresectable cholangiocarcinoma to be resectable. The aim of this article is to present the usefulness of adjuvant surgery in a case of advanced cholangiocarcinoma that was successfully treated with gemcitabine. A 72-year-old man was diagnosed with distal cholangiocarcinoma with liver metastases (cT2N0M1, Stage IV). He underwent metal stent placement in the duodenum to alleviate jaundice. After 18 courses of chemotherapy using gemcitabine without severe drug toxicities, a computed tomography scan showed that the liver metastases in S6 and S7 had disappeared. The patient underwent subtotal stomach-preserving pancreaticoduodenectomy and lymph node dissection. The pathological stage was pT2N0M0, Stage IB. The patient underwent 6 cycles of adjuvant chemotherapy using gemcitabine. The patient is alive and well 6 years and 9 mo after the diagnosis.