著者

Tetsutaro Matayoshi Takahiro Tabuchi Iwao Gohma Takahiro Shimizu

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.82, no.12, pp.2941-2942, 2018-11-24 (Released:2018-11-24)

参考文献数

9

被引用文献数

3

著者

Takahiro Shimizu Satoshi Watanabe Tomoaki Yoneda Masaki Kinoshita Nanao Terada Takafumi Kobayashi Kazuki Gohara Tetsuo Tsuji Hiroki Nakatsumi Yuichi Tambo Noriyuki Ohkura Miki Abo Johsuke Hara Takashi Sone Hideharu Kimura Kazuo Kasahara

出版者

Japanese Society of Allergology

雑誌

Allergology International (ISSN:13238930)

巻号頁・発行日

vol.71, no.2, pp.251-253, 2022 (Released:2022-04-21)

参考文献数

10

被引用文献数

8

著者

Youta Takano Makiko Shibano Yuuya Takizawa Eriko Arai Shinobu Koyama Takahiro Shimizu Takehisa Matsumoto

出版者

National Institute of Infectious Diseases

雑誌

Japanese Journal of Infectious Diseases (ISSN:13446304)

巻号頁・発行日

vol.76, no.2, pp.159-161, 2023-03-31 (Released:2023-03-24)

参考文献数

11

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Klebsiella oxytoca is an opportunistic pathogen that causes nosocomial infections. Here, we describe an unusual clinical strain of indole-negative K. oxytoca, GU175, isolated from the urine of a patient with cystitis. The GU175 strain was identified as K. pneumoniae with a probability of 99.40%, negative for indole production, and resistant to third-generation cephalosporins by using the MicroScan Walkaway 40 SI system with the Negative combo EN1 J panel. Biochemical characterization of this strain using lysine-indole motility medium was negative for indole production. However, identification tests using the MALDI Biotyper system and 16S rRNA gene sequence analysis revealed that GU175 is K. oxytoca. DNA sequence analysis of the tryptophanase operon comparing the GU175 strain with the revertant GU176 strain, which tested positive for indole, revealed a point mutation in the Shine-Dalgarno sequence upstream of tnaC in the GU175 strain. This is the first report of indole-negative K. oxytoca, which was attributed to a mutation in the DNA sequence of the tryptophanase operon isolated from a patient with a urinary tract infection. As indole-negative K. oxytoca can be misidentified as K. pneumoniae by biochemical characterization, clinical microbiologists should be aware of such misidentifications.

著者

Masao WATANABE Takahiro SHIMIZU Ryo TAKAGI

出版者

The Japan Society of Mechanical Engineers

雑誌

The Proceedings of International Symposium on Seed-up and Service Technology for Railway and Maglev Systems : STECH (ISSN:24243167)

巻号頁・発行日

pp._3D23-1_-_3D23-8_, 2015-11-09 (Released:2017-06-19)

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Urban railway lines, upon which large conurbations crucially depend, suffer from chronic congestion and prolonged travel times during peak hours, and improvement of capacity and reduction in travel times are desperately needed. Also, competition with other modes of transport is ever intensifying. These necessitate the realization of a very high performance railway, called in this paper as "ultra-convenient rail transport" (UCRT), which can provide services that much better fit individual passengers' needs. Because needs of the passengers are very diverse, so should the services provided by UCRT. This naturally leads to the conclusion that ultra-high frequency operation is essential for UCRT. In this paper, the authors present the discussions on possible new technologies that can be used to realize UCRT, and the impact they may have on the attractiveness of the services provided by the new railway system. The techniques upon which the authors would discuss in this paper are: (1) moving block signalling systems, (2) on-board turnouts and (3) soft coupling. In the discussion, the pure moving block system (PMB) which stands inside the so-called 'brick wall' assumption and the relative moving block system (RMB) that breaks the 'brick wall' assumption are compared, and significant improvements in performance may be achieved when RMB is combined with on-board turnouts. These techniques contribute to further reduction of headways between trains, and thus contribute to the realization of UCRT.