著者

Yutaka KAWAI Adil HASAN Go IWAI Takashi SASAKI Yoshiyuki WATASE

出版者

一般社団法人 電子情報通信学会

雑誌

IEICE Transactions on Information and Systems (ISSN:09168532)

巻号頁・発行日

vol.E95.D, no.12, pp.2852-2859, 2012-12-01 (Released:2012-12-01)

参考文献数

16

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In this paper we report on an approach inspired by Ant Colony Optimization (ACO) to provide a fault tolerant and efficient means of transferring data in dynamic environments. We investigate the problem of distributing data between a client and server by using pheromone equations. Ants choose the best source of food by selecting the strongest pheromone trail leaving the nest. The pheromone decays over-time and needs to be continually reinforced to define the optimum route in a dynamic environment. This resembles the dynamic environment for the distribution of data between clients and servers. Our approach uses readily available network and server information to construct a pheromone that determines the best server from which to download data. We demonstrate that the approach is self-optimizing and capable of adapting to dynamic changes in the environment.

著者

Yutaka Seino Kohei Kaku Nobuya Inagaki Masakazu Haneda Takashi Sasaki Atsushi Fukatsu Michito Ubukata Soichi Sakai Yoshishige Samukawa

出版者

The Japan Endocrine Society

雑誌

Endocrine Journal (ISSN:09188959)

巻号頁・発行日

vol.62, no.7, pp.593-603, 2015 (Released:2015-07-31)

参考文献数

20

被引用文献数

13 23

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Luseogliflozin, a selective sodium glucose cotransporter 2 inhibitor, was demonstrated in a previous 24-week study of type 2 diabetic patients to be efficacious and well tolerated. This study mainly aimed to evaluate the long-term safety of luseogliflozin monotherapy in Japanese type 2 diabetic patients based on the Japanese guidelines. Additionally, long-term efficacy was also evaluated. Patients on diet and exercise therapy alone with an HbA1c of 6.9-10.5% received luseogliflozin 2.5 mg once daily for 52 weeks. For patients with insufficient glycemic control, this dose was able to be increased to 5 mg at Week 24. Adverse events (AEs), clinical laboratory tests, vital signs and 12-lead electrocardiograms were used to assess safety. Efficacy endpoints consisted of changes in HbA1c, fasting plasma glucose (FPG), and body weight from baseline. Of 299 patients who received luseogliflozin, 279 completed the study. Most AEs were mild in severity with incidences of AEs and adverse drug reactions at 75.3% and 16.7%, respectively. Although hypoglycemia was observed in 7 patients (2.3%), no major hypoglycemic episodes occurred. The incidences of AEs of special interest, including pollakiuria, volume depletion and urinary tract/genital infections, were at acceptable levels. Luseogliflozin significantly lowered HbA1c (-0.50%, P< 0.001), FPG (-16.3 mg/dL, P< 0.001) and body weight (-2.68 kg, P< 0.001) at Week 52 compared to baseline. Up-titration to 5 mg further improved glycemic control. In this long-term study of Japanese type 2 diabetic patients, luseogliflozin monotherapy was well tolerated for 52 weeks and provided a sustained glycemic lowering effect and reduced body weight.

著者

Akihiko Kitamura Hiroshi Naito Takahiko Kimura Kazumitsu Shinohara Takashi Sasaki Haruhiko Okumura

出版者

一般社団法人 映像情報メディア学会

雑誌

映像情報メディア学会誌 (ISSN:13426907)

巻号頁・発行日

vol.69, no.10, pp.J292-J297, 2015 (Released:2015-09-25)

参考文献数

12

被引用文献数

6

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To establish the superiority of monocular presentation in augmented reality (AR) over binocular presentation, we report two experiments involving a tracing task with an AR image covering a visual field observed in both the monocular and binocular conditions. In Experiment 1, the subjective visibility of the AR image and the accuracy of the tracing task were measured. In Experiment 2, participants identified a character in the AR image while tracing. The AR image was less visible in the monocular condition than in the binocular condition. Hence, participants could observe the real world more easily in the monocular condition, and the resulting performance on the tracing task was better in the monocular condition. Information acquisition from the AR image in the monocular condition was equivalent to that in the binocular condition. These results exhibit the superiority of monocular AR presentation for the performance of manual tasks.