著者

岩坪 健 Takeshi Iwatsubo

出版者

同志社大学人文科学研究所

雑誌

社会科学 = The Social Science(The Social Sciences) (ISSN:04196759)

巻号頁・発行日

vol.43, no.4, pp.1-17, 2014-02-28

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楽器の中には、男性向け(または女性向け)の楽器がある。ジェンダーの考えによれば、男性性の楽器と女性性の楽器である。源氏物語には四種類の絃楽器が描かれている。それらを考察すると、男性性と女性性の楽器に分類できる。

著者

Kenichiro Sato Yoshiki Niimi Tatsuo Mano Atsushi Iwata Takeshi Iwatsubo

出版者

International Research and Cooperation Association for Bio & Socio-Sciences Advancement

雑誌

BioScience Trends (ISSN:18817815)

巻号頁・発行日

pp.2022.01115, (Released:2022-04-20)

参考文献数

18

被引用文献数

1

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Whether there are differences in the time to onset of drug-induced parkinsonism (DIP) depending on the type of drugs causing DIP remains uncertain, so that question was investigated here using a large real-world database. Fourteen DIP-related drug categories were defined to perform a disproportionality analysis using a large Japanese pharmacovigilance database containing more than 600,000 self-reported adverse events (AEs) recorded between April 2004 and September 2021 to identify AEs indicating "parkinsonism" in association with the defined drug categories. The time from drug administration to the onset of DIP was comparatively analyzed. Results indicated that the median time to onset was shorter than 1 month in more than half of the cases of DIP; it was shortest with peripheral dopamine antagonists (median: 0.1 weeks), followed by benzodiazepine (median: 0.5 weeks), butyrophenone (median: 0.7 weeks), novel antidepressants (median: 2.5 weeks), atypical antipsychotics (median: 3.3 weeks), other antidepressants (e.g., lithium, median: 3.7 weeks), and benzamide (median: 4.5 weeks). In contrast, anti-dementia drugs, tricyclic antidepressants, and antiepileptic drugs resulted in a relatively longer time to onset (median: 9.9, 17.2, and 28.4 weeks, respectively). In addition, a maximum delay of even longer than 2 years was reported for benzamide (846 weeks), anti-Parkinsonism drugs (382 weeks), phenothiazine (232 weeks), atypical antipsychotics (167 weeks), anti-dementia drugs (161 weeks), and benzodiazepines (120 weeks). The current results suggested that the characteristics of the time to onset of DIP may substantially differ depending on the type of drug causing that DIP. This finding may help when diagnosing patients with parkinsonism.

著者

岩坪 健 Takeshi Iwatsubo

出版者

同志社大学人文科学研究所

雑誌

社会科学 = The Social Science(The Social Sciences) (ISSN:04196759)

巻号頁・発行日

vol.50, no.4, pp.19-33, 2021-02-28

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同志社大学所蔵「源氏物語色紙」を翻刻して、現代語訳と解説を付けた。資料(Material)

著者

岩坪 健 Takeshi Iwatsubo

出版者

同志社大学人文学会

雑誌

人文學 = Doshisha University Jinbungaku (Studies in Humanities) (ISSN:04477340)

巻号頁・発行日

no.207, pp.63-88, 2021-03-15