著者

Ryosuke Taniguchi Juno Deguchi Takuya Hashimoto Osamu Sato

出版者

The Editorial Committee of Annals of Vascular Diseases

雑誌

Annals of Vascular Diseases (ISSN:1881641X)

巻号頁・発行日

pp.oa.18-00167, (Released:2019-05-08)

参考文献数

25

被引用文献数

13

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Objective: Open revascularization of the lower extremity in patients with chronic limb-threatening ischemia (CLTI) does not guarantee limb salvage. Due to the high prevalence of frailty among these patients, we hypothesized that sarcopenia negatively affects limb prognosis.Methods: Seventy-five CLTI patients who underwent open revascularization between 2011 and 2015 were retrospectively reviewed. The lumbar psoas index, which is the ratio of the cross-sectional area of the psoas major muscles to the patients’ height squared, was used as a surrogate marker for sarcopenia. Male and female patients were stratified separately according to lumbar psoas index values. The lower two-thirds of the population for each sex were defined as the sarcopenia group, with the higher third defined as the non-sarcopenia group.Results: Comorbidities and ambulatory status did not differ between the sarcopenia (n=50) and non-sarcopenia (n=25) groups. The sarcopenia group had significantly lower overall survival rates than the non-sarcopenia group (60% vs 87% at 3 years, P<0.05). Moreover, the limb salvage rates were significantly lower in the sarcopenia group than in the non-sarcopenia group (73% vs 100% at 2 years, P<0.05).Conclusion: Sarcopenia, as measured by the lumbar psoas index, may predict poor limb prognosis in CLTI patients undergoing open revascularization.

著者

Yoshiko Watanabe Yuuki Shimizu Takuya Hashimoto Toru Iwahashi Kunihiro Shigematsu Yoshikazu Nakaoka Masayoshi Harigai Japan Research Committee of the Ministry of Health Labour and Welfare for Intractable Vasculitis (JPVAS)

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-23-0211, (Released:2023-07-07)

参考文献数

37

被引用文献数

1

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Background: The latest demographics, clinical and living conditions, and comorbidities of patients with thromboangiitis obliterans (TAO) in Japan are unknown.Methods and Results: We conducted a retrospective cross-sectional survey using the annual database of the Japanese Ministry of Health, Labour and Welfare medical support system for patients with TAO between April 2013 and March 2014. This study included 3,220 patients (87.6% male), with current age ≥60 years in 2,155 patients (66.9%), including 306 (9.5%) patients aged ≥80 years. Overall, 546 (17.0%) had undergone extremity amputation. The median interval from onset to amputation was 3 years. Compared with never smokers (n=400), 2,715 patients with a smoking history had a higher amputation rate (17.7% vs. 13.0%, P=0.02, odds ratio [OR]=1.437, 95% confidence interval [CI]=1.058–1.953). A lower proportion of workers and students was seen among patients after amputation than among amputation-free patients (37.9% vs. 53.0%, P<0.0001, OR=0.542, 95% CI=0.449–0.654). Comorbidities, including arteriosclerosis-related diseases, were found even in patients in their 20–30 s.Conclusions: This large survey confirmed that TAO is not a life-threatening but an extremity-threatening disease that threatens patients’ professional lives. Smoking history worsens patients’ condition and extremity prognosis. Long-term total health support is required, including care of extremities and arteriosclerosis-related diseases, social life support, and smoking cessation.

著者

Shungo TAKANO Kiyoto SHIN-MURA Eiki NIWA Takuya HASHIMOTO Kazuya SASAKI

出版者

The Ceramic Society of Japan

雑誌

Journal of the Ceramic Society of Japan (ISSN:18820743)

巻号頁・発行日

vol.126, no.6, pp.482-487, 2018-06-01 (Released:2018-06-01)

参考文献数

32

被引用文献数

1 6

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Sr2MgMoO6−δ (SMM) is one of promising anode materials for direct internal reforming solid oxide fuel cells as its excellent performance has been demonstrated. However, it is necessary to be chemically compatible with the electrolyte material to realize the original performance. In this study, we investigate chemical compatibility between SMM and typical electrolyte materials (8% mol Y2O3–92% mol ZrO2; YSZ, 10% mol Sc2O3–1% mol CeO2–89% mol ZrO2; ScSZ, La0.9Sr0.1Ga0.8Mg0.2O3−δ; LSGM) and anode interlayer materials (Gd0.1Ce0.9O2−δ; GDC, Ce0.8La0.2O2−δ; LDC) under conditions for preparing SMM electrode and operation. SMM formed a reaction layer with all of the typical electrolyte materials studied. LDC was the only material for the interlayer that maintains chemical compatibility with SMM, though it forms the reaction layer with YSZ and ScSZ. From these results, this study clarifies that LSGM and LDC should be used as electrolyte and interlayer, respectively, when SMM is used as the anode.

著者

Takuya Hashimoto Junya Ako

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-18-0405, (Released:2018-04-28)

参考文献数

13

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The 67thAnnual Scientific Session and Expo of the American College of Cardiology (ACC) were held at the Orange County Convention Center, Orlando, from March 10–12, 2018. This meeting offered 2,700 accepted abstracts presented in oral and poster sessions by 2,100 experts and 37 Late-Breaking Clinical Trials and Featured Clinical Research presentations. This report introduces the key presentations and highlights from the ACC 2018 Scientific Session.