著者
Kenji Nakahama Hiroyasu Kaneda Koichi Ogawa Yoshiya Matsumoto Yoko Tani Tomohiro Suzumura Shigeki Mitsuoka Tetsuya Watanabe Kazuhisa Asai Tomoya Kawaguchi
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.61, no.7, pp.1039-1042, 2022-04-01 (Released:2022-04-01)
参考文献数
16
被引用文献数
3

A 68-year-old Japanese man was diagnosed with lung adenocarcinoma stage IVB. We introduced a first-line chemotherapy of four cycles of carboplatin and pemetrexed and pembrolizumab, followed by pemetrexed and pembrolizumab maintenance therapy. Approximately four months after anticancer therapy, a small nodule appeared in the right peripheral S3 lesion. After five months, the nodule was confirmed as a Mycobacterium tuberculosis (TB) nodule. We initiated anti-TB therapy without stopping pembrolizumab, and the right S3 nodule shrank immediately. This report supports the concurrent use of anti-TB treatment with an immune checkpoint inhibitor when the TB infection area is limited.
著者
Tetsuya Watanabe Hirotsugu Kaga
出版者
映像情報メディア学会
雑誌
ITE Transactions on Media Technology and Applications (ISSN:21867364)
巻号頁・発行日
vol.5, no.1, pp.2-7, 2017 (Released:2017-01-01)
参考文献数
22
被引用文献数
3

To determine the optimum size of a braille font, we conducted an experiment in which a popular Japanese braille font was printed at various sizes on capsule paper and read and rated by late blind people. The results show that braille printed at 16 to 19-point sizes was read faster and rated higher than that printed at smaller or larger sizes. These optimum sizes mostly coincide with those found for young congenitally blind people. A new finding was that many reading errors that stemmed from mistaking the range of braille cells were observed at larger sizes, 20 to 22-point sizes. This means that enlarging the font size is not necessarily beneficial for late blind people and optimum sizes should be strictly selected when doing so.