著者

Tsuyoshi MATSUBA Momoko CHIBA Khongsap Akkhavong Aporn Sisuraj Yutaka INABA

出版者

The Japanese Society of Health and Human Ecology

雑誌

民族衛生 (ISSN:03689395)

巻号頁・発行日

vol.71, no.6, pp.255-262, 2005 (Released:2010-06-28)

参考文献数

13

被引用文献数

1

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尿路結石症が多発するラオスにおいて,食習慣や生活習慣に関連する因子と疾患発症との関係を明らかにすることを目的に症例対照研究が行われた.尿路結石症例114名および病院ベースでマッチされていない対照97名が調査対象として選ばれた.質問紙を用いて食習慣や生活習慣に関する因子について質問され,各因子についてオッズ比が求められた.また食習慣に関しては,各々の摂取食品項目がどのような因子によって成り立っているのかを明らかにするため因子分析が用いられた.更に共分散構造分析(構造方程式)を用いて食習慣と疾患との間の関係についてモデルを構築しそれぞれの関連を明らかにした.尿路結石は病因の異なる2つのグループ,すなわち上位尿路結石および下位尿路結石に分けられる.下位尿路結石については伝統的な摂取食品項目との間に正の関連を表し,近代的な摂取食品項目との間には負の関連を示した.対照的に上位尿路結石は伝統的な食品項目よりも近代的な食品項目との問により高いパス係数が認められた.ラオスでは今後食生活の近代化によって,下位尿路結石は減少するものの上位尿路結石の罹患は上昇することが考えられる.

著者

Dongmei Qiu Michiko Kurosawa Yingsong Lin Yutaka Inaba Tsuyoshi Matsuba Shogo Kikuchi Kiyoko Yagyu Yutaka Motohashi Akiko Tamakoshi

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

vol.15, no.Supplement_II, pp.S157-S167, 2005 (Released:2005-08-18)

参考文献数

72

被引用文献数

27 43

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BACKGROUND: The objective of this article was to overview the epidemiology of pancreatic cancer. We summarize the results of the Japan Collaborative Cohort Study (JACC Study) and some previous studies.METHODS: References were mainly in a Medline search through Pub Med database. In addition, 3 papers about the JACC Study were quoted.RESULTS : In the JACC Study, the standardized mortality ratio of pancreatic cancer was 0.97 in females and 0.84 in males. Diabetes mellitus (DM) has increased the risk for pancreatic cancer in many studies. In the JACC Study, DM had a risk for pancreatic cancer in males (hazard ratio = 2.12). Cigarette smoking has been associated with pancreatic cancer in many studies. In the JACC Study, the hazard ratio for current smokers was 1.6 in males, and 1.7 in females. The ratio was 3.3 who smoked 40+ cigarettes/day in males. In the JACC Study, alcohol intake was not associated with pancreatic cancer. These results are consistent with the other studies. Coffee consumption has not been associated with pancreatic cancer in many studies. In the JACC Study, the hazard ratio significantly increased to 3.19 among men who consumed 4+ cups of coffee per day. The relationships between diet /nutrition and pancreatic cancer are not clear in many studies.CONCLUSION: The relation between smoking and pancreatic cancer is most consistently described. A further analysis of the relationships between family history, hormonal factors in females, dietary and nutritional factors, obesity, physical activity and pancreatic cancer is necessary.J Epidemiol 2005; 15: S157-S167.