- 著者
- Bing-jie Zheng Yue-ping Yin Zhi Xiang Yan Han Mei-qin Shi Ning Jiang Rui-xing Yu Xiang-sheng Chen
- 出版者
- 国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
- 雑誌
- Japanese Journal of Infectious Diseases (ISSN:13446304)
- 巻号頁・発行日
- vol.67, no.1, pp.17-21, 2014 (Released:2014-01-22)
- 参考文献数
- 30
- 被引用文献数
- 1 6
The objective of this study was to determine the prevalence of urethral Mycoplasma genitalium infections among male patients attending a sexually transmitted disease (STD) clinic in China and identify risk factors associated with this disease. A total of 423 patients were recruited in Hezhou City, Guangxi Province, China, and each was requested to complete a questionnaire regarding sociological and sexual behaviors. First-void urine samples were collected for M. genitalium analysis by polymerase chain reaction. Of the 406 urine samples collected, 114 were M. genitalium-positive, giving a prevalence rate of 28.1%. Univariate logistic regression analysis showed that M. genitalium infection was associated with younger age, having received at least senior high school education, and single marital status. In both univariate and multivariate logistic regression analyses, M. genitalium infection was found to be associated with lack of symptoms for STD in the past year (adjusted odds ratio [AOR] = 2.839; 95% CI = 1.495–5.392; P = 0.001), no use of condoms with steady partners in the past year (AOR = 2.830; 95% CI = 1.468–5.455; P = 0.002), and having sexual encounters with female sexual workers within the past 3 months (AOR = 2.955; 95% CI = 1.637–5.336; P < 0.0003). The observed high rate of M. genitalium infection among male STD patients in Hezhou City indicates an M. genitalium epidemic in the study population; thus, the national surveillance program and clinical health providers in China should more closely monitor this disease.
- 著者
- Ming NI Yan HAN Ray C. C. CHEUNG Xuemeng ZHOU
- 出版者
- The Institute of Electronics, Information and Communication Engineers
- 雑誌
- IEICE TRANSACTIONS on Electronics (ISSN:09168516)
- 巻号頁・発行日
- vol.E106-C, no.7, pp.417-426, 2023-07-01
This paper presents a hippocampal cognitive prosthesis chip designed for restoring the ability to form new long-term memories due to hippocampal system damage. The system-on-chip (SOC) consists of a 16-channel micro-power low-noise amplifier (LNA), high-pass filters, analog-digital converters (ADCs), a 16-channel spike-sorter, a generalized Laguerre-Volterra model multi-input, multi-output (GLVM-MIMO) hippocampal processor, an 8-channel neural stimulator and peripheral circuits. The proposed LNA achieved a voltage gain of 50dB, input-referred noise of 3.95µVrms, and noise efficiency factor (NEF) of 3.45 with the power consumption of 3.3µW. High-pass filters with a 300-Hz bandwidth are used to filter out the unwanted local field potential (LFP). 4 12-bit successive approximation register (SAR) ADCs with a signal-to-noise-and-distortion ratio (SNDR) of 63.37dB are designed for the digitization of the neural signals. A 16-channel spike-sorter has been integrated in the chip enabling a detection accuracy of 98.3% and a classification accuracy of 93.4% with power consumption of 19µW/ch. The MIMO hippocampal model processor predict output spatio-temporal patterns in CA1 according to the recorded input spatio-temporal patterns in CA3. The neural stimulator performs bipolar, symmetrical charge-balanced stimulation with a maximum current of 310µA, triggered by the processor output. The chip has been fabricated in 40nm standard CMOS technology, occupying a silicon area of 3mm2.