著者

Yasutaka Ishii Satoshi Sakaguchi

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.61, no.11, pp.1056-1064, 2003-11-01 (Released:2009-11-13)

参考文献数

38

被引用文献数

9 11

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Innovative carbon radical generation from hydrocarbons through a catalytic process under mild conditions has been achieved by the use of N-hydroxyphthalimide (NHPI) as a catalyst. This method can be successfully applied to a wide variety of functionalizations of hydrocarbons. Thus, alkanes are converted into alcohols, ketones, carboxylic acids, nitro alkanes and alkyl sulfonic acids through alkyl radicals generated by the action of NHPI. Hydroxysilylation was first performed by the addition of hydrosilanes and oxygen to alkenes bearing electron-withdrawing substituents. A new approach to oxyalkylation based on the concomitant addition of carbon radicals derived from alkanes or alcohols and molecular oxygen to alkenes or alkynes has been described.