著者
Xin XIA Xiaozhen ZHOU David LO Xiaoqiong ZHAO Ye WANG
出版者
The Institute of Electronics, Information and Communication Engineers
雑誌
IEICE Transactions on Information and Systems (ISSN:09168532)
巻号頁・発行日
vol.E97.D, no.7, pp.1769-1780, 2014 (Released:2014-07-01)
参考文献数
42
被引用文献数
1

A build system converts source code, libraries and other data into executable programs by orchestrating the execution of compilers and other tools. The whole building process is managed by a software build system, such as Make, Ant, CMake, Maven, Scons, and QMake. Many studies have investigated bugs and fixes in several systems, but to our best knowledge, none focused on bugs in build systems. One significant feature of software build systems is that they should work on various platforms, i.e., various operating systems (e.g., Windows, Linux), various development environments (e.g., Eclipse, Visual Studio), and various programming languages (e.g., C, C++, Java, C#), so the study of software build systems deserves special consideration. In this paper, we perform an empirical study on bugs in software build systems. We analyze four software build systems, Ant, Maven, CMake and QMake, which are four typical and widely-used software build systems, and can be used to build Java, C, C++ systems. We investigate their bug database and code repositories, randomly sample a set of bug reports and their fixes (800 bugs reports totally, and 199, 250, 200, and 151 bug reports for Ant, Maven, CMake and QMake, respectively), and manually assign them into various categories. We find that 21.35% of the bugs belong to the external interface category, 18.23% of the bugs belong to the logic category, and 12.86% of the bugs belong to the configuration category. We also investigate the relationship between bug categories and bug severities, bug fixing time, and number of bug comments.
著者
Yingjie Zhong Ye Wang Jun Guo Haifeng Chu Yong Gao Limin Pang
出版者
東北ジャーナル刊行会
雑誌
The Tohoku Journal of Experimental Medicine (ISSN:00408727)
巻号頁・発行日
vol.237, no.3, pp.183-191, 2015 (Released:2015-10-17)
参考文献数
55
被引用文献数
1 14

Juvenile idiopathic arthritis (JIA) is the most common arthritis in the adolescents under the age of 16. Etanercept, an inhibitor of tumor necrosis factor, is often used to treat JIA despite its significant side effects. Homeopathic remedies, such as blueberries, have anti-inflammatory properties with fewer unwanted effects and should be considered as a primary treatment. We aimed to explore the efficacy and safety of combination therapy of blueberry and etanercept for JIA. Two hundred and one JIA patients were selected, and randomly and evenly assigned to three groups: ETA (50 mg of etanercept twice weekly), ETABJ (matched etanercept and 50 ml blueberry juice daily) and ETAPJ (matched etanercept and placebo juice). The severity of JIA was measured using American College of Rheumatology scales (ACR) 20, 50 and 70. The levels of pro-inflammatory cytokines, interleukin-1 (IL1) alpha and IL1 beta, and interleukin-1 receptor antagonist (IL1RA) were measured by qRT-PCR and ELISA. After a 6-month follow-up, the ACR20, ACR50 and ACR70 in an ETABJ group were higher than those in other two groups (P < 0.05), suggesting clinically meaningful improvement in JIA. Meanwhile, the symptoms and side effects were reduced significantly or absent in an ETABJ group, including mental diseases, retrobulbar optic neuritis, gaining weight, infection, cutaneous vasculitis, diarrhea, uveitis and pancytopenia. Blueberries reduced the levels of IL1 alpha and beta, and increased the level of IL1RA. Thus, a combination therapy of blueberry and etanercept can reduce the severity of JIA and should be developed as a new method for JIA therapy.