- 著者
- Pin-Ying Wu Tetsuya Takemi
- 出版者
- Meteorological Society of Japan
- 雑誌
- SOLA (ISSN:13496476)
- 巻号頁・発行日
- pp.2021-024, (Released:2021-06-23)
- 被引用文献数
- 1
Identical twin experiments with and without topography are conducted with the Weather Research and Forecasting (WRF) model in an idealized framework to investigate the impact of topography on the initial error growth associated with moist convection. A topography is set as a single Gaussian shape mountain with a peak height of about 1000 m. Both experiments show clear diurnal cycles, while moist convection develops earlier and organizes to a larger size in the experiment with topography. To evaluate the initial error growth, a metric referred to as moist difference total energy (MDTE) is proposed to represent the differences between the two simulations in twin experiments. The horizontal spatial distribution, temporal evolution, and horizontal wavenumber space of the MDTE suggest that the error growth is greatly dominated by the different features of convection development between the two experiments. The analysis based on individual cloud areas shows that the convective clouds developing over the mountain have smaller MDTE at the early stage of development.
- 著者
- Pin-Ying Wu Tetsuya Takemi
- 出版者
- Meteorological Society of Japan
- 雑誌
- SOLA (ISSN:13496476)
- 巻号頁・発行日
- vol.17, pp.134-139, 2021 (Released:2021-07-30)
- 参考文献数
- 22
- 被引用文献数
- 1
Identical twin experiments with and without topography are conducted with the Weather Research and Forecasting (WRF) model in an idealized framework to investigate the impact of topography on the initial error growth associated with moist convection. A topography is set as a single Gaussian shape mountain with a peak height of about 1000 m. Both experiments show clear diurnal cycles, while moist convection develops earlier and organizes to a larger size in the experiment with topography. To evaluate the initial error growth, a metric referred to as moist difference total energy (MDTE) is proposed to represent the differences between the two simulations in twin experiments. The horizontal spatial distribution, temporal evolution, and horizontal wavenumber space of the MDTE suggest that the error growth is greatly dominated by the different features of convection development between the two experiments. The analysis based on individual cloud areas shows that the convective clouds developing over the mountain have smaller MDTE at the early stage of development.
- 著者
- Geng-Ruei Chang Yi-Shin Chiu Ying-Ying Wu Wen-Ying Chen Jiunn-Wang Liao Te-Hsin Chao Frank Chiahung Mao
- 出版者
- The Japanese Pharmacological Society
- 雑誌
- Journal of Pharmacological Sciences (ISSN:13478613)
- 巻号頁・発行日
- vol.109, no.4, pp.496-503, 2009 (Released:2009-04-17)
- 参考文献数
- 51
- 被引用文献数
- 105 122
Rapamycin (RAPA), an immunosuprpressive drug used extensively to prevent graft rejection in transplant patients, has been reported to inhibit adipogenesis in vitro. In this study, we investigated the anti-obesity effects of RAPA in C57BL/6J mice on a high-fat diet (HFD). Mice treated with RAPA (2 mg/kg per week for 16 weeks) had reduced body weight and epididymal fat pads/body weight, reduced daily food efficiency, and lower serum leptin and insulin levels compared with the HFD control mice. However, RAPA-treated mice were hyperphagic, demonstrating an increase in food intake. Dissection of RAPA-treated mice revealed a marked reduction in fatty liver scores, average fat cell size, and percentage of large adipocytes of retroperitoneal and epididymal white adipose tissue (RWAT and EWAT), compared to the HFD control mice. These results suggest that RAPA prevented the effect of the high-fat diet on the rate of accretion in body weight via reducing lipid accumulation, despite greater food intake. It is likely that RAPA may serve as a potential strategy for body weight control and/or anti-obesity therapy.
- 著者
- Qiang LIU Bo JIANG Li-Ping JIANG Ying WU Xiao-Guang WANG Feng-Ling ZHAO Bao-Hua FU Turai ISTVAN Enhai JIANG
- 出版者
- Journal of Radiation Research Editorial Committee
- 雑誌
- Journal of Radiation Research (ISSN:04493060)
- 巻号頁・発行日
- vol.49, no.1, pp.63-69, 2008 (Released:2008-02-01)
- 参考文献数
- 12
- 被引用文献数
- 47
On 26 April 1999, three persons were accidentally exposed by high dose 60Co irradiation. They suffered from severe (one case) or moderate (two cases) hemopoietic form of acute radiation sickness (ARS). As part of the comprehensive treatment, strict reverse isolation and granulocyte-macrophage colony-stimulating factor (GM-CSF) therapy were applied. All the patients recovered after an appropriate treatment for 83 days. In our experience, the correct diagnosis and effective treatment at an early stage proved to be helpful to the patients in pulling out from the critical stage of acute radiation sickness. To avoid menstruation by the female patient just in the critical stage, we modified her menstruation cycle by testosterone. In our view, GM-CSF should be given as early as possible with enough dosage for promoting early hematological reconstruction. The experience obtained from the medical management of these patients is valuable for the treatment of such patients in the future.