著者

Sung-Yong Choi Jung-Hyun Choi

出版者

The Society of Physical Therapy Science

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.28, no.3, pp.837-843, 2016 (Released:2016-03-31)

参考文献数

44

被引用文献数

3 11

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[Purpose] The purpose of this study was to examine the effects of cervical traction treatment, cranial rhythmic impulse treatment, a manual therapy, and McKenzie exercise, a dynamic strengthening exercise, on patients who have the neck muscle stiffness of the infrequent episodic tension-type (IETTH) headache and frequent episodic tension-type headache(FETTH), as well as to provide the basic materials for clinical interventions. [Subjects] Twenty-seven subjects (males: 15, females: 12) who were diagnosed with IETTH and FETTH after treatment by a neurologist were divided into three groups: (a cervical traction group (CTG, n=9), a cranial rhythmic contractiongroup (CRIG, n=9), and a McKenzie exercise group (MEG, n=9). An intervention was conducted for each group and the differences in their degrees of neck pain and changes in muscle tone were observed. [Results] In the within-group comparison of each group, headache significantly decreased in CTG. According to the results of the analysis of the muscle tone of the upper trapezius, there was a statistically significant difference in MEG on the right side and in CRIG on the left side. According to the results of the analysis of the muscle tone of the sternocleidomastoid muscle, there was a statistically significant difference in MEG on the right side and in CRIG on the left side. [Conclusion] In the comparison of the splenius capitis muscle between the groups, there was a statistically significant difference on the right side. Hence, compared to the other methods, cervical traction is concluded to be more effective at reducing headaches in IETTH and FETTH patients.

著者

山田 裕一 Yong CHOI Ki Joong KIM Ja Wook KOO Il Soo HA 後藤 治子 小笠原 信明

出版者

一般社団法人 日本痛風・核酸代謝学会

雑誌

プリン・ピリミジン代謝 (ISSN:09162836)

巻号頁・発行日

vol.19, no.1, pp.13-21, 1995 (Released:2012-11-27)

参考文献数

19

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Hypoxanthine guanine phosphoribosyltransferase(HPRT)が先天的にほぼ完全に欠損するとLesch-Nyhan症候群となる.Lesch-Nyhan症候群韓国人5家系におけるHPRT変異遺伝子を,ゲノムDNAの分析とRT-PCRによるmRNAの分析の2面から解析し,2例の新しい変異(533-9T→A,631delA)と3例のすでに報告のある変異(310insG,Q109X,289delGT)を同定した.また,Q109X,289delGTにおいては,すでに報告のある異常mRNAのほかにスプライシング異常から生じるエクソンスキップのある異常mRNAの存在を確認した.すべての家系において保因者診断を,2家系においては変異遺伝子の出生前診断を行なった.